Cudurka jeermiska ama xasaasiyadda "gluten" wuxuu keeni karaa dhaawac halis ah
Weligaa ma kuu ogolaatay inaad cagahaaga seexato oo aad marka hore ku xanuunsato kabuubka kadibna laga bilaabo qalabka xiirashada, biinanka-iyo irbadaha inta uu "soo toosay"? Dadka qaba xanuunka neeropathy waxaa ka mid ah noocyada dareemeyaasha - kabuubyo iyo xannuun xanuun leh - mar kasta. Oo waxaa jira caddayn sii kordheysa oo ah in xididada neuropathy ay ku xidhan tahay cudurada baruurta iyo dareenka gluten.
Qiyaastii 10% dadka cusub ee laga helay cudurka cagaarshow waxay ku dhacaan xaalad la xidhiidha dareemayaasha neerfaha , badiyaa neefopathy peripheral neuropathy (taas oo ah wax caadi ah) ama glaxen ataxia (taas oo ah mid aad u yar), daraasadaha ayaa muujinaya.
Dhanka kale, dareenka gluten ee aan caan ahayn wuxuu yahay xaalad cusub oo la aqoonsan yahay oo aan guud ahaan la aqbalin, mana jirto daraasad aan eegeynin xuubka neeropathy iyada oo ah xaalad caafimaad oo la xidhiidha. Si kastaba ha ahaatee, dhakhtarrada cilmi baarista ku sameeya mawduucan ayaa sheegaya in qulqulka iyo kabuubyada xagjirnimada ay ka mid yihiin calaamadaha xasaasiga ah ee ugu caansan.
Peripheral Neuropathy waxay ku lug leedahay Nerve Damage
Qulqulka, kabuubyada, iyo xanuunka neuropathy ee dhuunta guud ahaan wuxuu ka yimaadaa dhaawaca dareemayaasha ee gacmahaaga iyo lugaha. Dhaawaca dareemayaasha - iyo calaamadaha - guud ahaan waxay ka bilaabaan naabnaantaada ugu dheer, taas oo ah sababta aad u aragtid calaamadaha marka hore cagahaaga iyo suurtogalkaaga gacmahaaga.
Dareenka walaac leh (mararka qaarkood cagahaaga ama gacmahaagu waxay dareemi karaan qabow, ama kulul, ama jecel yahay in qofku ku qalqaaliyo qalab fiiqan) sida caadiga ah waxay ka bilaabaan bartamaha ugu fog waxayna ka shaqeeyaan gudaha, lugahaaga iyo gacmahaaga. Waxaad yeelan kartaa hal hal dareemo ama xanuunka badan.
Diabetesku waa sababta 1aad ee sababa neeropathy peripheral neuropathy tan iyo badh ka mid ah dhammaan dadka qaba cudurka macaanku waxay la kulmi doonaan waxyeelada dareemayaasha.
Si kastaba ha noqotee, xaaladaha baxnaaninta (cudur-sidaha ayaa ah qaab-dhiska cusbada) sidoo kale waxaa lala xiriiriyay neeropathy peripheral.
Peripheral Neuropathy Gluten-ku Xiran Xaaladaha qaarkood
Xaaladaha qaarkood, neuropathy-du wuxuu u muuqdaa mid la xiriirta isticmaalka gluten - gaar ahaan, difaaca anti-gluten dadka qaar ayaa soo saara jawaab celinta gluten.
Mid ka mid ah daraasadda, cilmi baarayaashu waxay baaritaan ku samaysay 215 bukaan oo qaba axonal neuropathy, oo ah nooc ka mid ah nuucyada nullopathy ee ku lug leh dhaawaca khatartaada, ama qaniinyada dareenka. Wadar ahaan 140 ka mid ahi waxay ahaayeen "idiopathic neuropathy," taasoo macnaheedu yahay inuusan jirin sabab caafimaad oo muuqaal ah oo loo yaqaan 'neuropathy peripheral'.
Cilmi-baadhayaashu waxay tijaabiyeen 140 qof oo loogu talagalay difaaca jirka ee gluten iyadoo la adeegsanayo baaritaano dhiig ah oo lagu baaro dhiigga , baaritaanka AGA-IgA , iyo imtixaanka AGA-IgG . Inkastoo baaritaanadaas aan loo maleyneynin inay si gaar ah u tahay cudurka baruurta, waxay ogaan karaan haddii jidhkaaga uu u muuqdo gluten inuu yahay hargab iyo inuu soo saaro unugyo difaac ah oo ka dhan ah borotiinka.
Boqolkiiba soddon boqolkiiba dadka la baadho - 47 qof - waxay yeesheen difaac sare ee gluten mid ama labadaba, marka la barbar dhigo 12% heerka difaaca jirka ee sareeya ee gluten ee guud ahaan tirada guud. Natiijooyinka tijaabada ayaa tilmaamaya in dadka ay dareemaan xasaasiyad gluten maaddaama khubarada qaarkood ay kugula talinayaan AGA-IgA iyo AGA-IgG sida baaritaannada xasaasiyadda gluten .
Cilmi-baadhayaashu waxay kaloo sameeyeen finankas iyo biopsies dadka ku jira daraasada looga shakisan yahay in ay qabaan cudurka baruurta (cholesterol) oo ay ku ogaadeen in 9% kuwa ku jira kooxda "neuropathy" aan dhab ahaantii haysanin xajiin. Hiv-DQ2 iyo HLA-DQ8 - ayaa laga helay 80% dhammaan dadka bukaanka qaba neuropathy.
Astaamaha Muhiimka ah ee Calaamadaha Cudurka ah ee Peripheral Neuropathy ee Celiac iyo Gluten
Peripheral neuropathy dhab ahaantii waa mid ka mid ah calaamadaha aan caadiga ahayn ee cilladda baruurta , sida laga soo xigtay Jaamacadda Chicago Celiac Center. Xaqiiqdii, waxaa suurtagal ah in aan lahayn calaamadaha caloosha oo la dareemi karo ee cudurka cirrooliga, laakiin halkii laga heli lahaa badi neuropathy iyo calaamadaha kale ee neerfaha.
Calaamadaha maskaxda ee sida neeropathy, xannuun iyo maskaxda maskaxda ayaa xitaa aad ugu badan dareenka gluten-ka ee aan caanaha lahayn, sida uu qabo Dr. Alessio Fasano, oo ka mid ah cilmi-baarayaasha hoggaamiya ee dareenka gluten-ka. Dr. Fasano wuxuu sheegay in ilaa 30% dadka uu ku dhaco dareemeyaasha gluten inay leeyihiin calaamadaha neerfaha ... boqolkiiba inta ka weyn dadka qaba calaamadaha cudurka neerfaha ee cudurka baruurta.
Haddii aad qabto neuropathy-ga xiniinyaha oo lagu ogaado bararka xasaasiyadda ama "gluten", waxaa laga yaabaa inaad awood u yeelatid inaad xoojiso ama xitaa xalliso calaamadahaaga adoo raacaya cunto-la'aanta aan cuntada-lahayn - daraasadaha qaarkood waxay heleen cuntada. Si kastaba ha ahaatee, daraasado kale ayaa ogaaday in "muujinta neerfaha," oo ay ku jiraan neeropathy peripheral, laga yaabo inuu sii wado ama xitaa horumariyo ka dib marka la ogaado, isagoo tilmaamaya in ay jiri karto geedi socodka bararsan ee la xidhiidha.
Jaamacadda Chicago waxay ku talinaysaa in dadka qaba cudurka neuropathy ee ay sababto cudurada baruurta ay hubiyaan inay kala tashadaan takhaatiirtooda ku saabsan joojinta daroogooyinka taasoo keeni karta neeropathy peripheral. Dhaqdhaqaaqayaasha waxaa kale oo ay kugula talinayaan in barojirrada nollopathy ay sameeyaan isbedel hab nololeed si loo yareeyo xanuunka, oo ay ka mid yihiin iska ilaalinta wakhti dheer socoshada ama socodka, xirashada kabaha dabacsan (xaaladaha qaarkood, caymiska waxaa laga yaabaa inuu kabo daweyn khaas ah), si loo yareeyo xanuunka iyo xanuunka.
Dhakhaatiirta ayaa sidoo kale awood u leh inay qoraan daawo yarayn kara qaar ka mid ah raaxo la'aanta ka dhalatey neuropathy-ka, gaar ahaan haddii aysan u muuqan inay ka jawaab celinayso cuntada aan lahayn gluten-free. Dhanka kale, dadka qaba neuropathy peripheral, haddii ama ay u muuqato in ay la xiriirto cudurka baruurta ama xasaasiyadda gluten, waa inay hubiyaan inay taxaddar dheeraad ah ka qaataan marka ay socdaan ama socdaan ilaa maaddaama aysan dareemeynin cagahooda ay keeni karaan halis .
Ilaha:
Chin R. et al. Peripheral Neuropathy iyo Celiac Cudurka. Fursadaha Daweynta ee hadda jira ee Neurology. 2005 Jan; 7 (1): 43-48.
Hadjivassiliou M. et al. Neuropathy oo ku xiran Dareenka Gluten. Journal of Neurology, Neurosurgery, iyo Cilmi-nafsiga. 2006 Nov; 77 (11): 1262-6. Epub 2006 Jul 11.
Rigamonti A. et al. Cudurka Celiac ee la soo Bandhigo Neerka Neerfuuriyaha: Saameynta Cunto-Cunto-bilaash ah. Musqusha iyo Neerarka. 2007 Maajo; 35 (5): 675-7.
Jaamacadda Chicago ee Xarunta Cudurka Dabaysha (Peripheral Neuropathy). Noocyada Cudurka Nooca 'Peripheral Neuropathy - Inflammatory - Cudurka' Celiac '.
Zelnik N. et al. Range of Neerologic Disorder ee Bukaanka qaba Cudurka Cagaac. Pediatrics. 2004 Jun; 113 (6): 1672-6.