In laguugu sheego in aad qabtid dyslipidemia waxay noqon kartaa cabsi. Si kastaba ha ahaatee, ereygan guud ee loo isticmaalo in lagu sheego in aad leedahay hal ama in ka badan oo ah xaddidaadyo ku saabsan astaantaada dabiiciga ah oo laga yaabo inuu aad u hooseeyo ama sareeyo. Nasiib wanaag, waxay ku xiran tahay noocyada lipids-ka ee ay saameeyeen, waxaa jira siyaabo badan oo lagu daaweyn karo xaaladdaan - oo ka mid ah qaadashada daawo si aad u sameysid dhowr isbedel hab nololeedkaaga.
Guudmarka
Dyslipidemia waa xaalad caafimaad oo loola jeedo heer aan caadi ahayn oo ah dhiig-yare. Nooca ugu caansan ee dyslipidemia waa hyperlipidemia ama heerarka lipid sare. Nooca kale ee aan caadi ahayn ee dyslipidemia, hypolipidemia, wuxuu loola jeedaa heerarka lipid ee aan caadi ahayn. Dyslipidemias waxay waxyeeli kartaa wax kasta oo ka mid ah astaanta lipid, oo ay ku jiraan heerarka LDL ee kolesteroolka, heerarka HDL ee kolestaroolka, triglycerides , ama isku-darka lipids kuwaas.
Marka heerarka kolesteroolka oo keliya ay sareeyaan ama hooseeyaan, tan waxaa loo yaqaan 'hypercholesterolemia' ama hypocholesterolemia, siday u kala horreeyaan. Mararka qaarkood, kuwani waxaa kale oo loo yaqaan 'hyperlipoproteinemia' ama hypolipoproteinemia. Marka triglycerides kaliya ay saameeyeen, tan waxaa lagu magacaabi karaa hypertriglyceridemia (heerarka triglyceride sare) ama hypotriglyceridemia (heerarka triglyceride hoose). Taa beddelkeeda, haddii qofku leeyahay heerarka triglyceride iyo cholesterol labadaba, tan waxaa loo yaqaan 'disorder' ama isku dhafan 'dislipidemia'.
Sababaha
Waxaa jira arrimo badan oo keeni kara dyslipidemia-kana mid ah cudurrada dhaxalka leh ee noloshaada. Sababaha dyslipidemia waxaa loo kala qaybin karaa laba qaybood oo waaweyn: dyslipidemia primary ama secondary.
Dyslipidemia (Primary dyslipidemia) waxa loola jeedaa heerarka lipid aan caadi ahayn oo keena hiddo-wata ama hiddo-wade laga dhaxlay hal ama labada waalidba.
Jeermiska cillada ah wuxuu keeni karaa nadiifin aan caadi ahayn ee lipids ama wax ka beddeli kara sida lipids-ka qaarkood loogu sameeyo jirka. Haddii cudurka dyslipidemia uu ku dhex jiro qoyska, cudurku wuxuu inta badan ku leeyahay ereyga "familial" magaciisa si uu u muujiyo inay tahay xaalad dhaxal ah. Shakhsiyaadka qaba dyslipidemias oo ku lug leh kordhinta LDL ayaa halis weyn u ah inay ku dhacdo atherosclerosis hore ee nolosha, taas oo horseedi karta jirrooyinka wadnaha oo dhicis ah.
Diablipidemia secondary, dhinaca kale, waa mid caadi ah waxayna dhacdaa sababo kala duwan oo ku lug leh qaybo gaar ah oo ku saabsan qaab nololeedkaaga ama xaalado caafimaad oo gaar ah oo aad qabto. Hyperlipidemias waxaa laga yaabaa inay sababto:
- Baruurta liidata ama sareeya, cuntada sonkorta sare leh
- Jimicsi la'aan
- Daawooyinka qaarkood sida beta blockers, daawooyinka qaarkood ee lagu daaweeyo HIV, iyo p-pillerka afka
- Cudurka beerka
- Ku xadgudubka khamriga
- Sigaar cabista
- Hypothyroidism oo aan la daaweyn
- Sonkorowga aan kontoroolka lahayn
Hypolipidemias secondary, kuwaas oo aan caadi ahayn, waxaa laga yaabaa inay keenaan hyperthyroidism aan la daaweyn ama kansarada qaarkood.
Calaamadaha iyo Calaamadaha
Ma jirto hab sax ah oo lagu ogaanayo inaad qabto dyslipidemia - ha ahaato hyperlipidemia ama hypolipidemia - haddii aadan qabin guddi lipid ah. Tani waxay ku lug leedahay dhiig oo laga soo qaado xafiiska dhakhtarkaaga oo laguu falanqeeyay heerarka LDL, HDL, iyo triglycerides.
Xaalado dhif ah oo ka mid ah lipids aad u sarreeya, ayaa kor u kacay, xameedka huruudka ah ee loo yaqaan 'kedthomas' ayaa laga yaabaa inuu muuqan karo jirka.
Daaweynta
Waxaa jira daawooyin kala duwan iyo tallaabooyin kale oo loo heli karo si wax looga qabto dyslipidemias.
Hypolipidemias looma daaweyn karo ilaa ay ka daran yihiin, badanaa xaaladaha qaarkood xaaladdan la dhaxlo. Qaar ka mid ah kiisaskaas, cuntada ayaa la bedelay, waxaana la qaadan karaa fiitamiino qaddar ah oo baruurta leh.
Daaweynta hyperlipidemias waxay ku xiran tahay heerka darnaanta dabeecada lipid, iyo sidoo kale nooca lipids ayaa saameynaya. Cunto-barar cunto-yareyn iyo hab-nololeedka ayaa badiyaa lagu taliyaa, waxaana ka mid ah joojinta sigaarka, kordhinta jimicsiga iyo wax ka qabashada xaaladaha caafimaad ee keeni kara heerarka sare ee lipid.
Xaaladaha qaarkood, daawooyinka ayaa sidoo kale loo isticmaalaa in lagu yareeyo lipids-kaaga iyo in la yareeyo khatarta cudurka wadnaha mustaqbalka.
> Ilo:
> Lam JYT. Manhajka Merck ee Daaweynta iyo Daaweynta.
> Fauci AS, Braunwald E, Kasper DL et al (eds). Mabaadii'da Harrison ee Mabaadii'da Daaweynta gudaha, daabacaadda 19-aad. New York, McGraw Hill, 2013.