Fursadaha ayaa ah in haddii aad leedahay heerar barar sare leh, waxay ka dhalanayaan waxyaabo caan ah oo loo yaqaan 'genetics, diet, jimicsi la'aan, da', iyo jinsi. Laakiin xaaladaha qaarkood, heerarka kolestaroolka sare waxaa sababi kara cudurrada kale ama daroogooyinka si ballaaran loo soo qoray.
Marka loo yaqaano hyperlipidemia labaad ama la helay, xaaladdan caadi ahaan waa natiijada cudur kale oo isbeddelaya astaanta lipid ee bukaanka.
Laakiin waxaad la kulantaa halis caafimaad oo ah heerarka sare ee kolestaroolka - istaroogga , wadna xanuunka , iyo cudurada wadnaha. Heerka sarreeya ee kolestaroolku wuxuu u baahan yahay in la maamulo iyadoon loo eegin asalkiisa.
Marka lagu daro halista la xusuusto, xiriirka ka dhexeeya asaasiga dhexe iyo kan labaad ee hyperlipidemia ayaa si gaar ah muhiim u ah marka heerarka triglyceride ee ugu sarreeya ay dhacaan xaaladaha qaarkood ee hyperlipidemia. Marka la isku daro, labadan xaaladood waxay u horseedi karaan xanuunka loo yaqaan 'pancreatitis' , oo ah caabuq ku yimaada beeryarro badanaa oo halis ku ah nolosha.
Xanuuno Caadi ah Heerarka Jirka ee Heerka sare leh
Maxay yihiin cudurrada keeni kara hyperlipidemia? "Sababta ugu xun ayaa ah macaanka iyo sonkorowga , waa cudurada lipid ugu badan ee waddankan," ayuu yiri Maureen Mays, MD, oo ah kaaliyaha cilmiga daawada iyo agaasimaha ka-hortagga cudurrada kahortagga Jaamicadda Caafimaadka iyo Sayniska Oregon ee Portland, Oregon.
"Waa arrin si toos ah ula xidhiidha cayilka waddankan," ayay raacisay.
Dhamaan "kolesterool" xun, ama lipoprotein hoose ( lDL ), qaybo waa isku mid, Mays wuxuu sharxayaa. Qaybaha LDL oo loo yaqaan qaybo yar oo caan ah LDL ayaa loo aqoonsan yahay in ay u badan tahay inay horseedi karaan atherosclerosis .
"Dadkaas qaba cudurka macaanku waxay leeyihiin heerar LDL ay u muuqdaan kuwo caadi ah, laakiin maaha," Mays ayaa sidaas yidhi. "Habka aad had iyo jeer aragto (helitaanka hyperlipidemia) waa triglycerides sare, HDL hooseeya, iyo wax yar oo cufan ah LDL."
Marka laga soo tago sonkorowga iyo cirridka, cudurada la xidhiidha hyperlipidemia waxaa ka mid ah:
- Hypothyroidism (qanjidhka fir-fircoon ee unugyada firfircoon)
- Cushing's syndrome (cudur keena heerarka sare ee cortisol hoormoonka)
- Kelyaha oo shaqo la'aan ah
- Nephrotic syndrome (xanuunka kalyaha)
- Alcoholism
- Qaar ka mid ah xanuunada dheef-shiid kiimikaad iyo dheef-shiid kiimikaad
- Anorexia nervosa
Xaaladaha ku qoran liiska dhammaantood waxay saameyn ku yeeshaan heerarka dhiigga ee kolestaroolka iyo triglycerides. Tusaale ahaan, hypothyroidism, iyo heerarka hoose ee hoormoonka thyroxine iyo triiodotyronin ayaa caadi ahaan saameyn ku yeelanaya kor u kaca kolesteroolka guud, "xun" kolesterool (LDL), triglycerides iyo lipids kale oo la xidhiidha cudurka wadnaha.
Xaaladaha kale, xiriirka ka dhexeeya cudurrada asaasiga ah iyo hindhiso-sidaha ayaa la fahamsan yahay. Xiriirka u dhexeeya anorexia nervosa, tusaale ahaan, iyo kolestaroolka sare wali waa la baaraa sababta oo ah dadka qaba anorexia waxay caadi ahaan qaadaan cunto aad u hooseeya ee "cholesterol".
Mukhaadaraadka iyo Qaadashada Hyperlipidemia
Daawooyinka qaarkood iyo daaweynta hoormoonka waxay la xiriiraan hurgunka la soo helay iyo isbeddellada kale ee heerarka dhiigga ee dhiigga. Estrogen iyo corticosteroids waxay kor u qaadi karaan heerarka triglycerides iyo "wanaagsan" kolestaroolka, ama HDL, halka steroids afka laga qaato ay inta badan hoos u dhigto heerarka HDL.
Kiniinada xakameynta dhalmada waxay kordhin kartaa heerarka kolestaroolka waxayna kordhin kartaa halista atherosclerosis, iyada oo ku xidhan nooca iyo qiyaasta progestin / estrogen.
Beta blockers , waa nooc daawooyinka loo qoro xaalado gaar ah, sida cadaadis dhiig oo sarreeya , glaucoma, iyo miyir-qabad, sida caadiga ah sare u qaadidda heerarka triglycerides iyadoo hoos u dhigeysa heerka HDL. Retinoids loo isticmaalo si loo maareeyo xaaladaha sida psoriasis iyo noocyada kansarka maqaarka qaarkood, ayaa mararka qaarkood lala xiriiriyaa kororka heerarka LDL iyo triglyceride.
Diyaalo yaryar ayaa loo qoraa si loo yareeyo hannaanka dheecaanka jidhka oo xad-dhaaf ah. Fasalka diuretics loo yaqaan 'thiazide diuretics' - ayaa badanaa la isticmaalaa si loo daweeyo cadaadiska dhiig karka - ayaa sidoo kale lala xiriiriyay heerarka kor u kaca kolesteroolka iyo triglyceride.
Waxaa jira cilmi baaris joogto ah sababtoo ah daraasadaha qaarkood waxay muujiyeen in qiyaasaha hoose ee diuretics ay la socdaan daroogooyinka kale ay yeelan karaan faa'idooyin saafi ah oo yaraynta xanuunka wadnaha.
Xaaladaha intooda badan, maareeynta cudurada hoosta, ama joojinta isticmaalka daroogada ee ku xiran hyperlipidemia, waxay u horseedi doontaa heerarka caafimaad ee "cholesterol" oo caafimaad qaba. Xaaladaha kale, daaweynaha si gaar ah loogu talagalay in la yareeyo heerarka kolesteroolka ayaa laga yaabaa in loo baahdo. Kuwan waxaa ku jiri kara isbeddelada hab-nololeedka, sida jimicsiga iyo cuntada, laakiin xaaladaha kale, daroogooyinka hoos u dhigi kara ayaa loo baahan karaa.
Qaad qaado
Ku guuldareysiga daweynta kiniiniyada hyperlipidemia waxaa lagu keeni karaa dhibaatooyin caafimaad oo halis ah. Sida Mays tilmaamayo, "Dhibaatooyinka dheef-shiid kiimikaadka ama macdanta laga helay waxay dhab ahaan halis dheeraad ah ugu yihiin cudurka wadnaha marka loo eego cudurada lipid-ka ee hooseeya."
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