Ciladda hurdada xad-dhaafka ah ee lagu aqoonsaday Polysomnogram iyo MSLT
Narcolepsy waa cudur dhif ah oo sababa hurdo badan oo maalintii ah . Ciladaha kale ee hurdada ayaa sidoo kale keena hurdo, oo ay ku jiraan apnea hurdada. Sidaa darteed, waxaa muhiim ah in la helo baaritaanka haboon ka hor inta aan la baarin daaweynta. Sidee loo yaqaan 'narkonka' oo lagu baaraa baaritaanada? Baro sida baadhitaanku ugu tiirsanaado tijaabooyinka hurdada ee caadiga ah oo ay ku jiraan polysomnogram iyo baaritaanka hurdada badan ee hurdo la'aanta (MSLT) iyo sida loo baadho.
Waa Maxay Narcolepsy?
Noocyada hurdo la'aanta, narcolepsy waa sababta labaad ee ugu badan ee hurdo-hurdo-darro badan maalintii ka dib markii la seexdo hurdo la'aan . Waa cillad ay ka kooban tahay sifooyin kala duwan. Marka laga reebo hurdada xad-dhaafka ah, waxaa sidoo kale jira luminta murqaha oo leh dareeno (oo loo yaqaan ' cataplexy' ), dhacdo muuqaal ah oo ku saabsan wakhtiga bilawga hurdo ( hallucinations hypnagogic ), iyo hurdo hurdo . Cataplexy waxay calaamad u tahay nooca 1 narcolepsy . Inkasta oo natiijooyinkan sifooyinkaas, saddexdii qofba mid ayaa dhammaantood leh afar calaamadood.
Cilmi-baadhista Narcolepsy
Haddii aad tuhunsan tahay in lagugu leeyahay qandho, waa inaad qiimaysaa dhakhtarkaaga iyo takhtarka takhasuska leh. Waxaa jira sababo kale oo hurdo badan, oo ay ka mid tahay inaanan helin hurdo ku filan, waana in la tixgeliyaa. Kadib qiimeyn taxadar leh iyo baaritaan, waxaa lagugula talin karaa barashada kale ee hurdada.
Heerka loogu talagalay baadhitaanka qanjidhada narkoonku waxay ku lug leedahay daraasad habeenimo ah oo la yiraahdo polysomnogram oo ay ku xigto imtixaan latency oo badan oo la seexdo (MSLT) maalinta xigta.
Maxkamaduhu waa in la joojiyaa isbuuca ka hor baaritaanka, iyo daawooyinka lidka diiqadda waa in la joojiyaa saddex toddobaad ka hor. Daawooyinkan, iyo ka noqoshada iyaga, waxay si kale u faragalin karaan natiijooyinka baaritaanka. Waxaa laga yaabaa in lagaa rabo in lagaa qaado baaritaanka mukhaadaraadka kaadida si loo hubiyo natiijooyinka baaritaanka inay sax yihiin.
Polysomnogram ayaa qiimeyn doona nooca hurdadaada. Muhiimad ahaan, waxay tilmaami doontaa sababaha kale ee suurtogalka ah ee hurdo-xumada aadka u daran, oo ay ku jiraan jirro kale oo hurdo sida hurdada hurdada, dhaqdhaqaaqyada wareega ee hurdada (PLMS), iyo dhibaatada dhaqanka REM . Hurdada hurdada ayaa ka badan inta badan nikotolepsi, daaweyntuna aad ayay uga duwan tahay.
Noocyada daawooyinka badanaa, polysomnogram waxay muujinaysaa hurdo la'aan , hufnaan yar oo yareyneysa, iyo hurdada REM ee dhacda 20 daqiiqo gudahood bilowga hurdada. Dadka caadiga ah ma seexaan hurdo REM illaa 80 illaa 100 daqiiqo kadib markii ay seexdaan. Narcoleptics si joogto ah ayaa loo qoraa inay hayso REM 60 daqiiqo ee ugu horreeya ee daraasaddooda hurdada.
Ka dib marka la dhammeeyo polysomnogram-ta, maalinta xigta tijaabo badan oo la seexdo (MSLT) ayaa la sameeyaa. In MSLT, ama dammaanad qaadashada, waxaa lagu siinayaa afar ama shan fursadood si aad u qaadato labadii saacadoodba mar. Qof caafimaad leh guud ahaan wuxuu seexanayaa 10 ilaa 15 daqiiqo, laakiin qofka qaba naasokolepsi waxaa laga yaabaa in uu hurdo yaraado 8 daqiiqo waxaana badanaa haysan doona hurdo REM ugu yaraan laba ka mid ah burooyinka. Haddii ay qabaan REM (SOREM) laba ama in ka badan oo ka mid ah miyir-qabadka, ama qaba polysomnogram-ta lagu ogaanayo, tani waxay si weyn u soo jeedinaysaa ciladda nikotepepsi.
Baaritaankee kale ayaa laga yaabaa inuu ku caawiyo baaritaanka nikotolepsy?
Waxaa jira dhowr imtixaan oo shaybaar ah oo laga yaabo in loo isticmaalo in lagu ogaado qandhada. Waxaa jira tijaabo hidde ah oo la yiraahdo DQB1 * 06: 02 (inkastoo aysan aheyn mid qumman oo laga yaabo inay sidoo kale ku fiicnaadaan dadka aan lahayn narkoon). Haddii baaritaanka hidda-socodku uu yahay mid aan fiicneyn, waxaa suurogal ah in qofku uu leeyahay narkobar.
Intaa waxaa dheer, haddii barashada hurdo la'aanta, mararka qaarkood waxaa laga yaabaa inay faa'iido leedahay in lagu tijaabiyo dheecaanka cerebrospinal leh habka lumbar puncture for orexin (ama heerarka hypocretin), oo tilmaamaya jiritaanka narkolepsi. Haddii heerarkan ay yaryihiin, ama xitaa eber, taasi waxay ka dhigeysaa calaamadaha qanjidhada.
Nasiib darro, imtixaankan lama helin waxaana laga yaabaa in loo baahdo in loo diro xarumo khaas ah, oo ay ku jiraan Jaamacadda Stanford.
Ilaha:
Akadamiyadda Maraykanka ee Hurdada Hurdada. "Qoondaynta caalamiga ah ee dhibaatooyinka hurdada." 2nd ed. 2005.
Carskadon, MA et al. "Tilmaamaha loogu talagalay baaritaanka hurdada badan ee hurdo la'aanta (MSLT): qiyaas caadi ah oo hurdo ah." Hurdo 1986; 9: 519.
Thorpy, MJ. "Narcolepsy." Continuum. Neurol 2007; 13 (3): 101-114.