Aromasin (Exemestane) waa daroogo muhiim ah oo loogu talagalay bukaanka kansarka sanbabada ee estrogen-positive. Laakiin, sida daroogo badan oo kansar ah, waxaa lagu soo rogaa ganacsiyada. Waxay ka caawisaa bukaanno badan inay ka hortagaan soo noqoshada kansarka naas-nuujinta ee hiddaha ah iyada oo xannibaysa wax-soo-saarka korontada ee jirka.
Laakiin qaadashada Aromasin waxay soo saartaa astaamaha menopausal : Nabarada kuleylka ah , daal, xanuun xanuun, iyo xitaa khafiifinta lafta.
Daraasad dhowaan la daabacay ayaa lagu daabacay The Lancet by koox cilmi-baadhis ah oncology Canada iyo America, eegaya saameynta Aromasin on lafta caafimaadka. Waxay soo gabagabeeyeen in "Exemestane uu ka sii darayo da'da la xiriirta da'da maadada macdanta qiyaas ahaan saddex jeer, xitaa marka la helo qadar ku filan iyo fitamiin D-ga."
Khasaaraha Cufnaanta Lafaha
Chemotherapy, iyo sidoo kale daaweynta hoormoonka dabiiciga ah, waxay sababi kartaa lafaha lafdhabarka (osteopenia) iyo mararka qaarkood marka haweeney qaadato aromatase inhibitor ka dib markii daaweynteeda koowaad, lafaheeda ayaa sii socon karta ilaa ay ka qabato osteoporosis . Tani luminta cufka iyo xoogga ayaa dhici karta xitaa haddii ay qaadato kalsiyum ku filan iyo Vitamin D si ay u ilaaliso caafimaadka lafaha.
Daraasada, oo uu hogaaminayey Dr. Angela Cheung, ayaa 242 haween ah oo ka weyn 2 sano ka soo raacday Aromasin (oo ka kooban). Dumarka oo dhan waxay lahaayeen baaritaan cufnaanta laf dhabarka ah midkoodna midkoodna ma qaadan daawada loo yaqaan osteoporosis.
Haweenkan waxa loo qaybiyay laba kooxood - mid ayaa qaaday Aromasin, qaar kalena waxay qaateen placebo. Inkastoo dhammaan haweenku muujiyeen khafiifinta lafaha dhammaadka laba sano, kooxda Aromasin ayaa ka sii dareysa cufnaanta lafahooda.
La Dagaalanka Dhibaatooyinka Dhaawacan
Dumarka intooda badani waxay lumiyaan lafaha lafahooda marka ay da'doodu yartahay, xitaa haddii aysan marnaba daweyn kansar ah.
Heerarka qanjirrada ayaa hoos u dhacaya xilliga menopause marka ay ugxan-yareenadu joojiyaan sameynta hormoonka haweenka. Qaadashada kalsiyumka iyo fitamiin D waxay kaa caawin kartaa dib u dhigista lafaha, iyo sidoo kale jimicsi culus. Haddii aadan u dulqaadan karin calcium carbonate aad u fiican, isku day in aad kalsiyum citrate halkii (waa sahlan tahay in lagu dheefsho). Dhakhtarkaagu wuxuu kugula talin karaa daawooyinka ka hortagga sida Fosamax ama Actonel, si uu u caawiyo daweynta lafaha lumitaanka . Waxa kale oo laga yaabaa inaad u baahato inaad hesho baaritaano lafdhabarka sanadka ah iyada oo qayb ka ah baaritaanadaada dumarka, si loola socdo caafimaadka lafahaaga.
> Isha:
> Cufka lafaha iyo qaab dhismeedka haweenka postmenopausal oo caafimaad qaba oo lagu daweeyo maaddada "exemestane" ee ka hortagga uur-qaadka koowaad ee kansarka naasaha: oo ah dhexdhexaad ah MAP.3 oo tijaabo ah oo la kala saaray. Dr. Angela M Cheung MD <, Lianne Tile MD, Savannah Cardew MD, Sandhya Pruthi MD, iyo al. Lancet Oncology - 7 Febraayo 2012.