Caddeynta iyo Ka Hortagga Dementia ee Ka-hortagga Xaaladaha
Daraasadihii ugu horeeyay waxay keentay farxad ku jirta beerta dementia ee ku saabsan xidhiidhka suurtogalka ah ee ka dhexeeya daroogada hoos u dhigtay daawooyinka loo yaqaan 'statins and dementia' . Hase yeeshee, daraasado dambe ma aysan soo koobin gabagabadii rajo-gelinta.
Daraasada Lancet waxay muujineysaa Khatarta Dementia oo hoos u dhacda
Bishii Nofembar 2000, daraasad lagu daabacay Lancet waxay ogaatay in shakhsiyaadka da'doodu ka weyn tahay 50 jir ee loo yaqaan 'statins' ay halis weyn ugu jiraan inay asaasaan cudurka .
Cilmi-baadhayaashu waxa ay barbar-dhigeen 284 qof oo waallida qaba ("kiisas") oo leh 1,080 "kantarool" oo aan samayn. Daraasad noocan ah waxaa loo yaqaanaa daraasad kiis-kumbuyuutareed. Shakhsiyaadka loo soo qoray statins waxay leeyihiin khatar aad u hooseeya marka loo eego kuwa aan ku qorin xayawaanka, xitaa marka ay dhacaan calaamadaha sida da'da, jinsiga iyo taariikhda wadnaha wadnaha. Natiijooyinka ayaa ahaa kuwo aad u sarreeya.
Daraasado Dheeraad ah ayaa ka soo horjeeda Aragtida Statins iyo Ka-hortagga Asaasaqa
Inkastoo daraasad labaad oo la daabacay 2004 ay ogaatay in dadka isticmaala Statin ay 39% hoos u dhacaan cudurka Alzheimers marka loo barbar dhigo dadka aan isticmaalin kuwa aan isticmaalin, taasi waxay sidoo kale ahayd daraasad kiis-kumbuyuutar ah. Sidaa daraadeed labadan barood ee macnahiisu ma ahan in statins ay yar tahay halista cudurka Alzheimers? Nasiib daro Maya.
Daraasada Cochrane ee qiimaynta nidaamsan ayaa muujisay laba daraasaad oo waaweyn oo lagu sameeyay isticmaalka dadka ku jira khatarta dadka khatarta ugu jira Alzheimer iyo jahwareer kale, oo ku lug leh wadarta 26,340 ka qaybgalayaasha.
Kuwaani waxay ahaayeen labadaba indho-indhayn oo la tijaabiyey tijaabooyin xakameyn xakameyn ah, oo ah nooca ugu saameynta daraasadda. Sababta oo ah daraasadaha koontoroolka kiisku dib u eegaan wakhtigooda oo aan la kala saarin, gabagabada laga soo qaado iyaga ayaa xaddidan. Daraasado laba-indho-indhogal ah ayaa wakhti hore la sugayaa, waxaa loo habeeyay si loo baaro cilmibaadhayaashu ma ogaan karaan kuwa bukaanka qaadanaya daroogada iyo kuwa qaadanaya placebo oo aad ugu haboon inay muujiyaan sabab iyo saameyn xiriir.
Bukaan-jiifka daraasaddan kowaad ee indho-indhoolka ah ayaa la raacay celcelis ahaan 3.2 sano, iyo kuwa daraasaddan labaad ee shan sano ah. Waxqabadka garashada ee dadka darsiga koowaad ah ayaa hoos u dhacay isla heerka. Daraasaddan labaad, ma jirin wax isbeddel ah oo ku yimid dhacdooyinka waallida oo u dhexeeya maaddooyinka laga helay statin iyo kuwa qaada kiniinada.
Marka la eego xoogga daraasaddan dambe, caddaynta in ay ka soo baxayso in statins ay ka hortagaan Alzheimer ama jahawareer kale oo shaki ah waqtigan.
Ilaha:
Macluumaadka Cochrane ee Dib-u-eegista Habeysan. 2016 Jan 4; 1: Statins for Ka-hortagga Asaasaqa. http://www.ncbi.nlm.nih.gov/pubmed/26727124.
Jick H, MD, Zornberg GL, MD, Jick SS, DSC, Seshadri S, MD, Drachman DA, MD. "Statins iyo Khatarta Asaasaqa." Lancet 2000 vol. 356, Issue 9242: 1627-31.
McGuinness B, Craig D, Bullock R, Passmore P. "Statins for Prevention of Dementia". Xogta Cochrane ee Falanqaynta Habraaca 2009, Issue 2.
Zamriini E, McGwin G, Roseman J. "Iskuduwaha Dhex-dhexaadinta Isticmaalka Xanuunka iyo Cudurka Alzheimer". Neuroepidemiology 2004; 23: 94-98.
- Waxaa ku qornayd Esther Heerema, MSW