Caadi ahaan, eosinophils waxay samaysaa ilaa hal boqol illaa saddex boqolkiiba dareenka dhiigga ee dillaaca (ie, wareegga unugyada dhiiga cad), ama 350 ilaa 650 millimitir cubic. Eosinophilia waxaa lagu qeexay sida dhiig badan oo eosinophils ah oo aan caadi ahayn. Eosinophilia waxaa loo tixgeliyaa mid fudud markii uu ka yar yahay 1,500 eosinophils per cubic millimeter, dhexdhexaad ah oo leh 1,500 ilaa 5,000 halkii millimitir cubic, iyo daran haddii ay jiraan wax ka badan 5,000 eosinophils per cubic centimeter.
Waxaa jira dhowr sababood oo macquul ah iyo xaalado la xiriira eosinophilia. Sababaha ugu caansan waxaa ka mid ah xaaladaha xasaasiyadda, cudurrada faafa, ama cudurada neoplastic (kansarka). Si aad u ogaatid sababta, taariikhda caafimaadka bukaanka iyo baaritaanka jirka waa lagama maarmaan, gaar ahaan siinta tilmaamo hore.
Daawooyinka badanaa waxay ka danbeeyaan falcelinta xasaasiyadda. Daawooyinka kasta ayaa masuul ka ah, laakiin badanaa daawooyinka antibiyootikada ama daawooyinka nonsteroidal anti-inflammatory (NSAIDs) waxay ku xiran yihiin eosinophilia peripheral. Marka uu xasaasiyadeeyo eosinophilic xasaasiyadeed, firiiric, xummad, iyo sambabada sambabada ayaa dhici karta.
Sababaha faafa ayaa badanaa lagu tuhunsan yahay bukaanada soo saaray eosinophilia ka dib markii ay ka soo baxeen dalka. Infakshanada Helminth waxaa la socda eosinophilia. Xaaladahan oo kale, oo loo yaqaan 'Loeffler's syndrome', waxa lagu gartaa sambabada sambabada oo leh eosinophilia iyadoo lagu jawaabayo gudbinta dirxiga helmin ee sambabada.
Caabuqyada fungal, infekshannada kale ee maskaxda, iyo tiibishada ayaa sidoo kale lala xiriiriyay eosinophilia.
Marka la eego kansarka sababo macquul ah eosinophilia, hematologic (dhiig) malignancies waxay noqon kartaa eosinophilic. Iyadoo lymphoid neoplasms, waxaa jiri kara eosinophilia reactive. Eosinophilia-peripheral ayaa sidoo kale laga yaabaa inay ku dhacdo qalqal jidheed oo adag.
Eosinophilia ayaa sidoo kale lala xiriiri karaa xaaladaha qaarkood ee cudurrada unugyada unugyada , Sjogren's syndrome iyo rheumatoid arthritis . Waxaa jira noocyo kala duwan oo isdabamarin, barar, ama xaalado nidaam ah oo laga yaabo inay la xiriiraan eosinophilia. Inkasta oo xaaladahaan guud ahaan loo tixgeliyo sababo caadi ah eosinophilia, takhaatiirtu waa inay tixgeliyaan suurtogalnimada. Bal aynu eegno dhowr ciyaaryahan.
Eosinophilic Granulomatosis Iyadoo Polyangiijis
Eosinophilic granulomatosis leh polyangiitis, xaalad hore loo yaqaan Churg-Strauss syndrome, ayaa lagu tilmaamay inuu yahay vasculitis systemic. Cudurka, sida laga soo xigtay Xarunta Johns Hopkins Vasculitis Center, ayaa markii ugu horreysay lagu sharraxay 1951, Dr. Jacob Churg iyo Dr. Lotte Strauss oo loo yaqaan 'Astesma', eosinophilia, qandho, iyo "dheecaan u socda nidaamyada unugyada kala duwan."
Eosinophilic Fasciitis (aka Diffuse Fasciitis Iyadoo Eosinophilia)
Eosinophilic fasciitis waa cudur naadir ah kaas oo maqaarka iyo nudaha maqaarka ka hooseeya maqaarku uu noqdo mid xanuun leh, barara, oo barara, oo si tartiib ah u adkaata gacmaha iyo lugaha. Tijaabadu waxay ku tiirsantahay maqaarka maqaarka iyo fascia (nudaha adag ee xajinta sare ee murqaha iyo muruqyada). Sababtoo ah adkeynta iyo adkaynta dabeecadda, waa in laga soocaa scleroderma .
Daaweynta eosinophilic fasciitis caadi ahaan waxay ku lug leedahay isticmaalka corticosteroids (badanaa prednisone afka). Inkastoo aan la ogeyn, waxaa muuqata inay dhacdo xaalad degdeg ah oo ku lug leh xaalado badan.
Eosinophilic Myalgia Syndrome
Eosinophilia Myalgia syndrome waa cudur aan caadi aheyn oo eosinophils oo badanaa keena caabuqa dareenka, muruqyada, iyo unugyada isku xiran. Waxaa ka mid ah xanuunka, finan, barar, qufac, iyo daal, muruq xanuun daran oo sii xumaanaya waa cabashada ugu weyn. Xaaladda ayaa markii hore la cayimay sannadkii 1989 , ka dib markii lala xiriiriyay caafimaadka, L-tryptophan.
Lacagta dheeriga ah ayaa la mamnuucay laakiin maaha ka hor intaan dadka dhintay. Waxaa jira kiisaska eosinophilic myalgia oo aan la xiriirin L-tryptophan.
Hypereosinophilic Syndrome
Hypereosinophilic syndrome waxaa lagu gartaa dhiig baxa eosinophilia, oo leh in ka badan 1500 eosinophils per millimeter cub oo soconaya ilaa lix bilood ama ka badan, taasoo keenaysa ka qayb qaadashada nidaamka nidaamka laakiin aan lahayn xayawaan, xasaasiyad, ama sabab kasta oo muuqda eosinophilia. Calaamaduhu waxay ku xiran yihiin xubnaha ay ku lug leeyihiin. Tijaabadu waxay ku lug leedahay sababaha kale ee eosinophilia, iyo sidoo kale dhuuxa lafta iyo baaritaanka cytogenetic. Daaweyntu badanaaba waxay ku billowdaa horgal.
Ilaha:
Eosinophilia: Tilmaamaha Qiimaynta ee Diinta ee Cudurka Rheumatologis. Akuthota et al. Rheumatologist Juun 15, 2015.
http://www.the-rheumatologist.org/article/eosinophilia-a-diagnostic-evaluation-guide-for-rologists//
Xarunta Johns Hopkins Vasculitis Center. 08/08/2015.
http://www.hopkinsvasculitis.org/types-vasculitis/churgstrauss-syndrome-css/
Eosinophiic Fasciitis. Rula A. Hajj-ali, Hagaha Merck MD. 08/08/2015.
http://www.merckmanuals.com/home/bone-joint-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/eosinophilic-fasciitis
Hypereosinophilic Syndrome. Jane Liesveld, MD iyo Patrick Reagan, Buugga Tilmaamaha Merck. 08/08/2015.
http://www.merckmanuals.com/professional/hematology-and-onologology/eosinophilic-disorders/hypereosinophilic-syndrome