Dheefaha Caafimaadka, Isticmaala, iyo More
N-acetylcysteine waa antioxidant oo lagu iibiyo foomka dheeraadka ah. Sidoo kale loo yaqaan 'N-Acetyl Cysteine' (ama NAC), N-acetyl-cysteine waxaa lagu beddelaa jirka oo loo yaqaan 'amino acid called cysteine. Taas bedelkeeda, daweyntu waxay ka caawisaa abuuritaanka glutathione, antioxidant oo kaalin muhiim ah ka sameeya xakamaynta shaqooyinka badan ee gacanta iyo waxay ka caawisaa habka difaaca jirka . Bixiyeyaasha waxay ku andacoodaan in qaadashada N-acetylcysteine supplements ay ka badbaadin karto dhibaatooyin caafimaad oo ballaaran.
Isticmaala
Daawada kale, N-acetylcysteine ayaa la sheegay in ay ka caawiso xaalado kala duwan.
- bronchitis
- Dhibaatada joogtada ah ee sanbabada (COPD)
- cirrhosis
- cystic fibrosis
- kolestarool sare
- HIV iyo AIDS
- Cudurka Lou Gehrig
Intaa waxaa dheer, taageerayaasha qaarkood waxay ku andacoodaan in N-acetylcysteine ay kaa caawin karto kahortaga kansarka.
Gargaarka Caafimaadka
Ilaa hadda, taageerada cilmi-baarista ee faa'iidooyinka N-acetylcysteine ayaa ka maqan. Halkan fiiri qaar ka mid ah natiijooyinka cilmi-baarista ee muhiimka ah:
1) Bronchitis joogto ah
N-acetylcysteine waxay kaa caawin kartaa in aad ku ilaaliso boronkiitada daba-galka ah ee jeegga, sida uu qabo warbixinta 2000 ee Daaweynta Klinikada . Ka fiirinta xogta laga soo bilaabo siddeed tijaabo caafimaad, qoraallada warbixinta ayaa ogaaday in isticmaalka muddada dheer N-acetylcysteine ay ka caawin karto kahortaga foosha ba'an ee boronkiitada daba dheer iyo, marka loo eego, kharashka daryeelka caafimaad ee hooseeya.
Waxyaabo badan: Qalabka dabiiciga ah ee Bronchitis
2) Sonkorow
N-acetylcysteine ayaa laga yaabaa inay caawiso maaraynta sonkorowga, waxay soo jeedinaysaa daraasad 2006-ka ka soo baxday Qorshaha Fiisiyeynta Asaasiga ah iyo Daaweynta Farqiga .
Ku biiridda 32 bukaan oo leh nooca 2 diabeteska iyo 15 koontarool oo caafimaad qaba, daraasaddan ayaa lagu ogaaday in saddex bilood oo daaweyn ah N-acetylcysteine ay gacan ka geysato nidaaminta glutathione heerarka bukaanka. Qorayaasha cilmi-baaristu waxay soo jeedinayaan in nidaamyada glutathione ay ka caawin karaan inay ka hortagaan dhibaatooyinka sonkorowga keena waxyeelo xagjir ah oo lacag la'aan ah.
Waxyaabo badan: Cudurada Dabiiciga ah ee Sonkorowga
3) Polycystic Ovarian Syndrome
N-acetylcysteine ayaa laga yaabaa inay caawiso daaweynta cudurrada ugxan-sidaha ah (PCOS), sida laga soo xigtay daraasad 2007-dii ka soo baxday Acta Obstetricia et Ginecologica Scandinavica . Hal wareeg oo caadada ah, 573 bukaanno PCOS ah ayaa lagu daweeyay citrate-koodh (kaniiniga sida badan loo isticmaalo uur-qaadidda). Marka xigta, 470 bukaan-socodka bukaan-socodka ah ayaa isku-dar ah N-acetylcysteine iyo citrifen citrate ah oo loogu talagalay wareegga caadada. Natiijooyinka daraasaddu waxay muujisay in sicir-bararka si fiican loo hagaajiyay ka dib marka lagu daro N-acetylcysteine.
Eeg sidoo kale: Qalabka dabiiciga ah ee PCOS
4) Cystic Fibrosis
N-Acetylcysteine waxay leedahay saameyn wax ku ool ah oo ku saabsan sambabada dadka dhexdooda leh fayruska cystic, sida laga soo xigtay warbixinta 1999 ee Acta Paediatrica . Warbixinta xogta laga helay 23 daraasadood, qorayaasha warbixintu waxay ku soo gabagaboobeen in aysan jirin caddayn ku filan oo lagu taageerayo isticmaalka N-Acetylcysteine ee daaweynta faybriska cysticis. Si kastaba ha ahaatee, qoraaga warbixinta ayaa sheegay in isticmaalka muddada dheer ee N-acetylcysteine uu keeni karo qaar ka mid ah hagaajinta hawsha sanbabada ee bukaanka cystic fibrosis.
5) COPD
Bukaannada qaba xasillooni xasillan oo dhexdhexaad ah (COPD), N-acetylcysteine waxay gacan ka geysan kartaa hagaajinta waxqabadka jirka.
Daraasad 2009 ah oo lagu daabacay joornaalka Chest , 24 bukaanjiifka COPD ayaa waxay qaateen N-acetylcysteine ama maalin kasta mudo lix bilood ah. Kadib qaadashada labo-jibbaar (si loo baabi'iyo N-acetylcysteine oo ka timaadda xubnaha ka qaybgalayaasha kooxda daaweynta), ka qaybqaatayaasha daraasadda ayaa loo wareejiyay daaweynta kale lix asbuuc oo dheeraad ah. Natiijooyinka daraasadda ayaa muujiyay in N-acetylcysteine ay ka caawisay hagaajinta calaamadaha caafimaadka ee neefta, sida awoodda sanbabada iyo adkeysiga jimicsiga.
Qabashada
Wax yar ayaa laga yaqaanaa amaanka isticmaalka muddada-dheer ee N-acetylcysteine.
N-acetylcystein waxay dhalin kartaa tiro saameyn ah, oo ay ku jiraan lallabbo, shuban iyo matag.
Maxay tahay, N-acetylcysteine waxay kordhin kartaa heerarkaaga homocysteine (amino acid oo ku xiran cudurka wadnaha). Haddii aad qaadatid N-acetylcysteine, waxaa muhiim ah in aad si joogto ah u hubiso heerarka homocysteine.
Qaar ka mid ah munaasabadaha qumman ayaa lagu soo sheegay daraasaadka xayawaanka (sida caadiga ah qiyaasta sare), sida sambabada sambabada iyo suuxdinta.
Waxaa intaa dheer, N-acetylcysteine waxay la macaamili kartaa daawooyin badan (oo ay ku jiraan daawooyinka cadaadiska dhiigga qaarkood, daawooyinka hoos u dhigaya nidaamka difaaca, daawooyinka kansarka, iyo daawooyinka xanuunka foosha ku haya).
Cabbiraadaha looma baarin nabadgelyo iyo sababtoo ah xaqiiqada ah in cuntada dheellitirka badanaa aan loo qoondeeynin, waxyaabaha ka mid ah alaabooyinka qaarkood way ka duwanaan karaan waxa ku qoran calaamadda badeecada. Sidoo kale maskaxda ku hay in badbaadada dheeraadka ah ee haweenka uurka leh, hooyooyinka kalkaaliyaha, carruurta, iyo kuwa qaba xaaladaha caafimaad ama kuwa qaadanaya daawooyinka aan la dhicin. Waxaad heli kartaa talooyin dheeraad ah oo ku saabsan isticmaalka dheeraadka halkan .
Iyadoo loo adeegsanayo Caafimaadka
Sababtoo ah la'aanta cilmi-baarista taageerada, waa mid aad u dhakhso badan oo kugula talin kara N-acetylcysteine wixii xaalad ah. Inkastoo N-acetylcystein ay bixiso faa'iidooyin caafimaad oo gaar ah, is-daaweynta dhibaatada caafimaad ee joogtada ah ee dheeraadka ah N-acetylcysteine waxay yeelan kartaa cawaaqib xumo caafimaad. Haddii aad ka fekereyso inaad qaadato N-acetylcysteine, la hadal dhakhtarkaaga ka hor inta aadan bilaabin xoojinta canshuurta.
> Ilo:
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> Grandjean EM, Berthet P, Ruffmann R, Leuenberger P. "Waxtarkii N-Acetylcysteine ee Waqtiga Nafaqada Cudurka Dhiigheerka ah: Meta-falanqeynta La -Cajinta Labaad ee Lagu Kajiro, La-Qabsashada Kalkaaliyeyaasha Daaweynta Klinikada." Clin Ther. 2000 Feb; 22 (2): 209-21.
> Xarunta Kansarka Ku-meel-gaarka ah. "N-Acetylcysteine". Janaayo 2011.
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> Stav D, Raz M. "Saameyntii N-Acetylcysteine ku saabsan Calaamadaha Hawada ee COPD: Daraasad Dhex-dhexaad ah oo Kala-Xakameysan." Laabta. 2009 Aug 136 (2): 381-6.
> Jaamacadda Maryland Medical Center. "Cysteine"