Hoos u dhaca unugyada dhiigga cad ayaa badanaa la xiriira infakshanka
Lymphopenia (oo sidoo kale loo yaqaanno "lymfocytopenia") waa erey loo adeegsado sharaxaadda gobolka oo aanad haysan nooc ka mid ah unugyada dhiigga ee loo yaqaan 'lymphocyte'. Lymphocytes waa mid ka mid ah saddex nooc oo unugyada dhiigga cad (oo loo yaqaanno "leukocytes") oo laga helay dhiig. Leukocytes waxay u shaqeysaa qayb ka mid ah difaaca jidhka ee ugu horreeya ee jidhka ka hortaga cudurada keena cudurada keena sida bakteeriyada, fayruusyada, iyo dulinka.
Lymphopenia waxaa badanaa keena infekshin, oo ay ka mid yihiin hargabka caadiga ah, badanaaba wuu ka soo kabanayaa marka infekshanku uu ciribtiro. Xaaladaha ay sababtu tahay idiopathic (oo aan la garaneyn), waxay soo jeedin kartaa xaalad halis ah.
Fahmidda Lymphocytes iyo Lymphopenia
Inta badan unugyada dhiigaaga ku jira ayaa ah xeryaha (unugyada dhiigga cas) oo mas'uul ka ah gaadiidka oksijiinta ee jirka oo dhan. Tani waxaa la socda trombocytes (trombo-yada) iyo leukocytes.
Leukocytes waxaa lagu sameeyaa dhuuxa lafaha oo si xor ah u wareega dhiigga iyadoo qayb ka ah nidaamka difaaca jirka. Lymphocytes ayaa ka dhigan qaybta ugu weyn ee unugyadaas, iyada oo meel kasta ka jirta 25 iyo 45 boqolkiiba.
Lymphocytes ayaa lagu sii dari karaa saddex qaybood:
- Unugyada dabiiciga ah (NK) ee u adeega sida safka hore ee difaaca habka difaaca jirka
- T-unugyada oo la soo saaro si loo helo jawaab-celin qoto-dheer
- B-unugyada soo saara unugyada difaaca jirka kuwaas oo caawiya unugyada kale si ay u aqoonsadaan una gartaan jirooyinka
Sidan oo kale, lymfopenia waxaa lagu ogaan karaa nooca lymphocyte. Tusaale ahaan, HIV wuxuu si gaar ah u bartilmaameedsanayaa CD4 T-yada caabuqa, taas oo keentay khasaare weyn oo ka yimaada unug gaar ah. Dhimashada unugyada B-du waxay ku xiran tahay daawooyinka difaaca jirka (sida kuwa loo isticmaalo dadka qaata xubnaha) marka laga reebo NK-wareerka caadi ahaan waa xaalad naadir ah.
Sababaha Lymphopenia
Lymphopenia waxaa sababi kara xaalado badan, oo ay ku jiraan infakshanka iyo waxyeellada daawada. Marmarka qaarkood, xaaladdu waxay saameyn kartaa oo kaliya saamiga lymphocytes. Dadka kale, waxay noqon kartaa natiijada ka dhalata dhammaan unugyada dhiiga cad.
Tusaale ahaan, marka daaweynta cagaarshowga nooca fayrasku (viral hepatitis) waxaa ka mid ah peginterferon iyo ribavirin, waxay sababi kartaa nutrophils (nutropenia) ama kaliya lymphocyte (lymphopenia) dadka qaarkood. Dadka kale, waxay saameyn kartaa dhammaan qaybaha unugyada dhiigga cad (leukopenia).
Lymphopenia ayaa inta badan lala xiriiriyaa xaaladaha saameynaya dhuuxa lafaha, oo ay ku jiraan:
- Cudurada viral oo si ku meel gaar ah u jahawareeraya hawlaha dhuuxa lafta
- Ciladaha dhididka ee ku lug leh hawlgalka dhuuxa lafdhabarta
- Kansar ama cuduro kale oo dhaawiciaya dhuuxa lafta
- Ciladaha maskaxda ee burburiya unugyada dhiigga cad ama unugyada lafta lafta
- Infakshannada ba'an ee dila unugyada dhiiga cad ayaa si dhakhso ah uga baaraandegi kara
- Daawooyinka, sida antibiotics, kuwaas oo burburin kara unugyada dhiiga cad
Cudurada ama Xaaladaha la Xidhiidha Lymphopenia
Cudurada iyo xaaladaha inta badan la xiriira lymphopenia ayaa si ballaaran loogu sharxi karaa inay noqdaan cudurada (cudur la xiriira infakshinka), cytotoxic (sunta ah unugyada), dhalasho (oo ay keento cilladda hidde), ama nafaqo.
Waxaa ka mid ah:
- Dhiig-xinjirowga (xaalad naadir ah oo uu jidhku joojiyo soo saaridda unugyada dhiiga)
- Chemotherapy
- HIV
- Hypersplenism (burburkii hore ee unugyada dhiigga ee beeryarada)
- Leukemia (nooc ka mid ah kansarka dhiigga)
- Lupus (xanuunka dhirta unugyada)
- Nafaqo daro iyo nafaqo la'aan
- Cudurrada Myelodysplastic (koox cudur ah oo carqaladeeya soo saarida unugyada dhiiga)
- Rheumatoid arthritis (xanuunka kale ee difaaca jirka)
- Daweynta shucaaca
- Qaaxada
Waa maxay tirakoobka unugyada dhiigga ee caddaanka ah ee caddaanka ah ee noo sheega
Tirada unugyada dhiigga cad ee hooseeya ayaa badanaa la ogaadaa marka dhakhtarkaagu amro tijaabinta xaalad aad horay u soo kulantay.
Tirada hooseysa waa ay yar tahay raadinta aan la filayn.
Xaaladaha qaarkood, nooca unugyada dhiigga ee saameynaya ayaa ku filan inuu ku tuso jihada cudurka. Waqtiyada kale, waxaad u baahan kartaa baadhitaano dheeraad ah si aad isu geyso sabab.
Tirada unugyada cad ee dhiigga oo aad u hooseeya ayaa ka dhigaya meelo aad halis ugu jirto caabuq. Haddii ay taasi dhacdo, waxaad u baahan kartaa inaad qaadato taxadar gaar ah si looga hortago cudurka. Tani waxaa ka mid ah ka fogaanshaha dadka kale ee jiran kara, gacmahaaga si joogto ah oo si fiican u dhaqaya, ama xitaa xiran maaskaro waji leh haddii aad ku jirto meel bannaan (sida diyaarad) dadka kale.
> Isha
- > Janeway, C .; Socodka, P.; Walport, M .; et al. Immunobiology (5th ed.) New York iyo London: Sayniska Garland; ISBN 0-8153-4102-6.
- > Regent, A .; Autran, B .; Carcelain, G .; et al. "Lymphocytopenia Idiopathic CD4: sifooyinka qalliinka iyo difaaca jirka iyo dabagalka 40 bukaannada." Daawada. 2014; 93 (2): 61-72.