Waxyaabahan Antibodies wuxuu Saameeyn Karaa, laakiin Kama Heli Karo Hormo Qalitaanka Qanjirka
Antibiyootigyada waa borotiino ay soo saaraan jirkaaga oo ka jawaab celiya ama isku dayaya in ay burburiyaan antigens, kuwaas oo ah walxo, sida fayrasyada iyo bakteeriyada, in jidhku aqoonsado sida ajnabigaa.
Xaaladaha qaarkood, jidhkaaga ayaa si khalad ah u tilmaamaya qanjidhada, unugyada, iyo xubnaha sida shisheeye. Nooc-celinta noocan ah waa dabeecadda cudur-sidaha 'autoimmunee s' , iyo kuwan difaaca jirka, oo bilaabaya weerar aan toos aheyn oo ku saabsan jirka qofka, waxaa loo yaqaannaa antibodies.
Hal dabeecad oo ah unugyada difaaca oolka ah ayaa ah unugyada difaaca jirka ee tirtiridda thyroid (TPO) , iyo joogitaankooda ("firfircooni") waxay soo jeedinayaan jiritaanka cudur tayroodh ah, oo badanaa Hashimoto's thyroiditis.
Fahmitaanka Hashimoto ee Thyroiditis
Hashimoto's thyroiditis, difaaca TPO wuxuu weerari karaa qanjirkaaga qanjirka.
Waqti ka dib, antibiyootooyinka TPO waxay keenaan barar iyo ugu dambeyntii ay burburin karaan dhammaan ama qeyb ka mid ah qanjirkaaga qanjirka. Maadaama dheef-shiid kiimikaadka uu sii yaraanayo inuu soo saaro hoormoonka tayroodhka, waxaa si tartiib tartiib ah u noqon kartaa hypothyroid. Hashimoto ee unugyada difaaca waxay sidoo kale sababi kartaa qanjirkaaga inuu abuuro nodules, ama uu noqdo mid aad u ballaaran, oo loo yaqaana gofer.
Xitaa markaa, waxay qaadan kartaa wakhti ay saameyn xun ku yeelan karto qanjirkaaga si aad uga muuqatid heerka baaritaanka hormoonada hormoonada ee hormoonada (TSH). Maaha wax aan caadi ahayn, xaqiiqda ah, in la helo difaaca jirka ee TPO mudo bilo ama sanado ah ka hor inta heerkaaga TSHu u kordho ilaa heer lagu ogaado cudurka hypothyroidism.
Waxaa muhiim ah in la sheego, sidoo kale, in dadka qaarkiis aysan waligood horay ugu sii soconin inay noqdaan hypothyroid, inkastoo ay qabaan difaaca jirka ee TPO.
Tijaabada Caafimaadka ee TPO, caadi ah TSH: Daaweyn Dammaanad?
Guud ahaan, haddii natiijada baaritaanka QM ay caadi tahay (inta u dhexeysa 0.4 iyo 4.5 cutubyada caalamiga ah ee halkii litir, ama mU / L), daaweyn (oo leh daroogada bedelka hormoonnada hormoonka ah) maahan wax damaanad ah, xitaa haddii difaaca TPO uu yahay mid wanaagsan.
Si kastaba ha noqotee, haddii qadarkaagu uu yahay mid sahlan (aynu dhahno qiyaastii 6.0mU / L) iyo hormoonkaaga thyroxine (T4) waa caadi, "saameynta" ee difaaca jirka ee TPO ayaa dhakhtarkaaga ku dhejin kara bilowga daaweynta hoormoonka tayroodhka. Tani waa sababta oo ah daaweynta hore waxaa laga yaabaa inay ka hortagto horumarka bukaanka ee loo yaqaan 'hypotyroidism subclinical hypothyroidism'.
Dhaqtarkaaga ayaa xitaa noqon kara mid aad u badan inuu ku daaweeyo hypothyroidism-gaaga haddii aad leedahay calaamado sida daal, calool-gal, ama niyad-jabka, ama aad qabtid cudur kale oo infalawanso ah, tusaale ahaan cudurka baruurta.
Da 'da, sidoo kale, ayaa door ka qaadan doona go'aanka dhakhtarkaaga. Caadi ahaan, waxaa jira marxalad sare oo loogu talagalay in lagu bilaabo daaweynta beddelidda hormoonka tayroodka ee dadka waaweyn, sababtoo ah asalkooda TSH ayaa ah xadka ugu sarreeya ee caadiga ah.
Ereyga
Qeybta hoose ee halkan waxaa weeye in habka difaaca jirka ee thyroid peroxidase (positive) uu tilmaamayo habsocod ah ootimmo; Si kastaba ha noqotee, waxay yihiin halis yar oo ah qanjidhada thyroid oo guud ahaanna ma dhihin haddii aad u baahan tahay ama aad u baahan tahay daaweynta hoormoonka tayroodhka. Taa bedelkeeda, waxay saameyn ku yeelan karaan adiga iyo go'aanka dhakhtarkaaga, oo ka mid ah arrimaha kale sida da'da, taariikhda qoyska, iyo astaamaha.
Guud ahaan waxa ugu wanaagsan inaad kala hadashid dhakhtarkaaga wixii ku saabsan natiijooyinka shaybaarkaaga iyo astaamaha.
Sidan ayaad ku xaqiijin kartaa inaad ku wanaajinayso caafimaadkaaga guud iyo caafimaadka guud.
> Ilo:
> Braverman, L, Cooper D. Werner & Ingbar's The Thyroid, 10-aad. WLL / Wolters Kluwer; 2012.
> Davies TF. Caabuq-xuubka Hashimoto's thyroiditis (xanuunka qanjirka 'autoimmune thyroiditis'). Ross DS, ed. UpToDate. Waltham, MA: UpToDate Inc.
> Garber, J, Cobin, R, Gharib, H, et. al. "Tilmaamaha Tababarka Caafimaadka ee loogu talagalay Hypothyroidism ee Dadka Qaan-Gaarka ah: Cosponsored by American American of Endocrinologists Clinical Association iyo Ururka Tiriida ee Maraykanka." Tababarka Indhaha. Vol. 18 No 6 Noofembar / Disembar 2012.
> Jonklaas J et al. Tilmaamaha loogu talagalay Daaweynta Hypothyroidism: Waxaa diyaariya Wakaaladda American Thyroid Association oo ku saabsan Beddelaadda Qanjidhka Qanjirka 'Thyroid'. Tirada . 2014 Dec 1; 24 (12): 1670-1751.
> Kent, Athol. "Qanjiraha Antibiyootikada ee Ku Xidhnaa Dhicinta iyo Dhalashada Ilmaha." Baadhitaanada Dhalmada iyo Ginecology 4.3-4 (2011): 128-129. 2011.