Ma jiraan wax tijaabo ah oo ku saabsan cudurka Parkinson?
Hada iminka ma jiraan baaritaano si cad u cadeeyn kara Cudurka Parkinson . Cilad-sheegiddu waxay ku saleysan tahay natiijooyinka baaritaanka ee dhakhtarkaaga oo lagu darayo warbixintaada calaamadaha aad la kulantid.
Xaaladaha uu qof weyni soo bandhigo astaamaha caadiga ah ee Parkinson's iyo waxay u jawaabaan daaweynta dopamine ee daaweynta, waxaa laga yaabaa inaan loo baahnayn wax faa'iido ah oo baaritaan dheeraad ah ama sawirid.
Baaritaan dheeraad ah ee Parkinson's
Xaaladaha kale, ee laga yaabo in laga yaabo in cudurka cudurka uu yahay mid cad, dadka yaryar ayaa saameynaya, ama waxaa jira calaamado qallafsan sida tufaaxa oo saameynaya labada gacmood ama laga yaabo in aysan jirin wax tayo ah, baaritaan dheeraad ah ayaa laga yaabaa inuu ku caawiyo. Tusaale ahaan, sawir-qaadiddu waxay door-bideen kaalin ay ku kala duwanyihiin iskudhafka muhiimka ah iyo Parkinson. Waxa kale oo ay muhiim u tahay in la xaqiijiyo waxa ugu horeysa ee lagu ogaanayo bukaan-eegtada Parkinson ka hor inta aan la qaadin habka daweynta ee loo yaqaan 'DBS' (dareenka qoto dheer ee maskaxda)
MRI ee tijaabada baaritaanka Parkinson
Mid ka mid ah tijaabooyinka caadiga ah ee la sameeyo intii lagu guda jiray qalabka neerfaha ayaa ah baaris MRI ah waxaana laga yaabaa inuu u malaynayo in baaritaanka cudur maskaxda saameeya sida Parkinson's, imtixaankan imtixaanka ayaa noqon doona mid lagama maarmaan ah. Xaaladda cudurka Parkinson, si kastaba ha ahaatee, MRI ma aha mid waxtar leh. Waxay eegaysaa qaab dhismeedka maskaxda kaas oo ujeedooyin kastoo xooggan, waxay u muuqdaan caadi ahaan cudurkan.
MRI ayaa laga yaabaa, si kastaba ha noqotee, in la muujiyo marka calaamaduhu ay ka muuqdaan dadka da'da yari (in ka yar 55 sano) ama haddii sawirka daaweynta ama horumarka calaamadaha aan la mid ahayn kuwa Parkinson. Xaaladahaan, MRI waxaa loo isticmaali karaa in lagu xakameeyo cudurada kale sida istaroogga , burooyinka , hidde-qabadka (maskaxda barar) iyo Wilson's Disease (cudur ka yimaada soo-ururinta bakteeriyada oo keeni karta jahawareer shakhsiyaad yar).
Sawirka Gaarka ah
Sawirada khaaska ah sida baaritaanka PET iyo DaTscans ayaa ah mid "shaqeynaya" oo badan. In kasta oo MRI loogu talagalay sawiridda maskaxda ee maskaxda, baaritaannadani waxay na siiyaan macluumaad ku saabsan sida maskaxdu u shaqeyso. DaTscans waxay isticmaashaa wakiilo la isku duro oo asal ahaan ka muuqda unugyada dareemayaasha dopamine-ka soo saaro iyaga oo ku xiraya iyaga. Kamarad gaar ah waxay u oggolaaneysaa in xooga la saaro wakiilka sawirada. Wakiil ka badan ayaa lagu ogaadey meelo gaar ah oo maskaxda ka mid ah, cufnaanta sare ee unugyada dopamine-abuurka ah ama nuuroonada iyo sidaas darteed, heerka sare ee dopamine laftiisa. Dhibaatooyinka ku lug leh heerarka dopamine aan caadi ahayn sida Parkinson's, waxaa jiri doona firfircooni yar oo dopamin ah. Inkasta oo tani ay waxtar ku yeelan karto kala duwanaanshaha maskaxda ee uu saameynayo Parkinson iyo yiraahdo, istiraatiijiga muhiimka ah ee heerarka dopamine waa caadi, ma caawineyso in la kala saaro Parkinson ee ka yimaada parkinsonisms kale sida nidaamyada kala duwan ama ciribtirka faafa .
Baaritaanada PET ayaa sidoo kale bixiya macluumaad ku saabsan hawlaha maskaxda waxayna kaa caawin karaan in la ogaado xanuunada kala duwan ee neurodegenerative sida cudurka Parkinson. Laakiin marka laga reebo DaTscans, waxay sidaas sameeyaan iyagoo eegaya sida maskaxdu u isticmaasho glucose.
Qaababka khaaska ah ee isticmaalka gulukoosku waxay u egtahay jirro kala duwan . Si kastaba ha ahaatee, baaritaannada PET, si kastaba ha ahaatee, waxaa loo isticmaalaa in ka badan goobta cilmi-baarista ka badan goobaha caafimaadka.
Qeybta hoose waxay ka duwan tahay sida xaaladaha kale ee cudurka sida dhiig karka ama sonkorowga , ma haysanno baaritaan qeexan oo lagu ogaanayo Cudurka Parkinson. Inkasta oo sawirku uu caawin karo daaweeyayaasha si loo xaqiijiyo baaritaanka Parkinsonism marka uu jiro shaki sababo kale, ma kala saari karo cudurka Parkinson cudurada kale ee sababaha kale ee parkinsonism. Ugu dambeyntii, farsamooyinka sawir qaadistu waxay faa'iido u leeyihiin oo keliya marka la eego qiimeynta bukaan-socodka khibrad u leh dhakhaatiirta qibrada leh iyo kaliya kiisaska la xushay, waxay saameyn doontaa maamulka.
Waxaan rajeyneynaa, caddaynta ujeeddooyinka lahaan la'aanta ah ee isbedeleysa mustaqbalka dhaw, iyadoo rajo-gelinta biomarkers ay isbeddelayaan sida aan u ogaanno loona daaweeyo cudurkan.
Tixraacyada:
Hauser, Robert A., MD. "Cudurka Parkinson." Cudurka Parkinson . Medscape, 21 Jan. 2014. Web. 27 Febraayo 2014.
Okun, Michael S., MD. "Miyaan ku helayaa Daahfur ama Baadhitaanka PET si loo xaqiijiyo Dareenkayga Cudurka Parkinson?" Asaasiga Qaranka ee Parkinson - . Machadka National Parkinson, 1 Febraayo 2011. Web. 26 Febraayo 2014.
Zhang, Linyuan, MD, iyo Jun Liu, MD. "Doorka Dhiig-baxa ee Daaweynta Cudurka Parkinson." Wargeyska Caalamiga ah ee Isku-dhafanaanta Daaweynta 1.11 (2013): 1-5. Intech . Web. 26 Febraayo 2014.