Statins waxaa badanaa loo isticmaalaa in lagu daaweeyo heerarka sare ee kolestaroolka LDL . Waxay hoos u dhigaan waxsoosaarka kolestaroolka beerka iyadoo la xakameynayo qodobka barxada durugsan. Waxyeellada xun ee daawooyinka dabiiciga ahi waxay tahay inay leeyihiin awood ay ku dheehan karto dhaawaca beerka. Waxyeellada dhinaca xun ee la taaban karo waa in ay yareeyaan khatarta ah inuu ku dhaco kansarka mindhicirka .
Tusaalooyinka Statins
Tusaalooyinka alaabada waxaa ka mid ah Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Pravachol (pravastatin), Crestor (rosuvastatin), iyo Zocor (simvastatin).
Sidee Ayay Wax Looga Heli Karaa Xaaladaha Kansarka Kansarka Kansarka?
Statins waxay leedahay saameyn badan oo jirka ah. Waxay yihiin pro-apoptotic, taageeraya habka jabinta unugyada, oo ay ku jiraan unugyada burooyinka. Waxay yihiin anti-angiogenic, u dhaqmaan si looga hortago kansarrada in ay sameeyaan dhiig. Iyadoo aan lahayn dhiig, burooyinka ma kori karaan oo ku duugi karaan unugyo kale. Waxay dareemaan unugyada burooyinka ee waxqabadka unugyada dabiiciga ah (NK). Tani waxay sii wanaajin doontaa ficilkaaga jirka jirka ee weerarka iyo dilida burooyinka iyagoo aqoonsanaya iyaga oo ah unugyo shisheeye oo aan loo oggolaan inay sii wadaan koritaanka jirka. Dhammaantood waxay u ekaanayaan sifooyin kuwaas oo saameyn ku yeelan kara burooyinka iyo kansarrada guud ahaan. Su'aashu waxay tahay haddii ay jiraan caddayn qancin ah in mawduucyada dhabta ahi ay saameyn ku leeyihiin ka hortagga kansarka oo ku faafaya jirkaada.
Cilmi-baaris lagu taageerayo Dacwadan
Daraasad Israeli ah oo lagu ogaaday in isticmaalka dhirta 'statins' in ka badan shan sano ayaa hoos u dhigi karta khatarta ah inuu ku dhaco kansarka mindhicirka illaa 50%.
Daraasaddan waxaa ka mid ahaa in ka badan 3,000 oo qof, qiyaas ahaan kala bar dadka qaba kansarka mindhicirka. Taasina waxay u muuqatay inay tahay raadin weyn.
Daraasad Canadian ah ayaa lagu ogaaday in isticmaalka 'statins' ay hoos u dhigtay khatarta ah inuu ku dhaco kansarka mindhicirka. Laakiin, qorayaasha ayaa tilmaamaya in qiyaastii 4,814 qof ay u baahanyihiin in lagu daaweeyo caadooyinka muddo shan sano ah si looga hortago hal kiis oo ah kansarka mindhicirka.
Taasi waa qadar aad u ballaaran oo daaweyn ah oo lagu sameeyo rajada laga qabo in laga hortago tiro yar oo ka mid ah kiisaska dhabta ah ee kansarka.
Cilmi-baaris aan taageernin Dacwadan
Daraasad Maraykan ah ayaa baaray xiriirka ka dhexeeya daroogooyinka hoos u dhiga kolesteroolka iyo jiritaanka kansarka mindhicirka ee ka badan 130,000 oo qof. Cilmi-baadhayaashu waxay ogaadeen in daroogooyinka hoos u-dhacaya, guud ahaan, saameyn kuma yeelan khatarta kansarka mindhicirka. Waxay si gaar ah u qeexeen in daraasaddu aysan taageersanayn fikradda ah in statins, sida daroogada daroogada ah, ay si weyn u yareeyso khatarta ah inuu ku dhaco kansarka mindhicirka ama malawadka.
Si kastaba ha ahaatee, taniyo daraasaddu ma aysan baari karin noocyo gaar ah oo ka mid ah mawaadiicda, ma ayan suurtogelin karin suurtagalnimada in noocyada gaarka ah iyo qiyaasaha dawooyinka ay dhici karto inay yareeyaan khatarta ah inuu ku dhaco kansarka mindhicirka.
A 2015 dib u eegis daraasad lagu soo gabogabeeyey, "weli lama xaqiijin in statins saameyn ku yeelanayso in la horumariyo kansarka mindhicirka, kansarka naasaha, ama kansarka sanbabada."
Khadka hoose
Miyuu dhirbaaxo yareeyo khatarta qofku u leeyahay inuu ku dhaco kansarka mindhicirka ama maahan? Nasiib darro, xeerbeegtadu weli way ka baxaysaa su'aashaas. Hadda, waa inaanu degno "maya" oo aan isha ku hayno cilmi baaris dheeraad ah. Su'aashu waxaa laga yaabaa in lagu xaqiijiyo hal waddo ama mid kale mustaqbalka.
Ilaha:
Stryjkowska-Góra A, Karczmarek-Borowska B, Góra T, Krawczak K. "Statins iyo kansarrada." Contemp Oncol (Pozn) . 2015; 19 (3): 167-75. doi: 10.5114 / wo.2014.44294. Epub 2014 Aug 29.
Hillmer, M. iyo Juurlink, D. " Sababtoo ah Statins ma yareeyaan Khatarta Kansarka Xiidanka?" Ururka Caafimaadka Canadian Journal 173.7 (Sebtembar 2005). 1 Sep. 2006.
Jacobs, E. iyo Rodriguez, C. " Calaamadaha ' Statins and Cancer Cancer Cancer' ee Mareykanka '' Journal of National Cancer Institute 98.1 (Jan. 2006): 69-72. 20 Jan. 2006.
Whitworth, Ariel. " Maandooriyeyaasha Hoos-u-Dhiman ee aan La Jirin Khatarta Kansarka Kansarka Kansarka Yar. " Jaangooyada Machadka Kansarka Qaranka 98.1 (Janaayo 2006): 1. 20 Jan. 2006.