Fahamka kala duwanaanta Afrika (Endemic) iyo Sportadic Burkitt Lymphoma
Maxay tahay lymphoma Burkitt, maxay yihiin sababaha, iyo sidee loo daaweeyaa?
Guudmarka
Burkitt's lymphoma (ama Burkitt Lymphoma) waa nooc aan caadi aheyn Non-Hodgkin Lymphoma (NHL) . Burkitt's lymphoma wuxuu caadi ahaan saameeyaa carruurta. Waa nooca aadka u daran ee laf-dhabarka ee B-cell kaas oo inta badan bilaabmaya oo ku lug leh qaybaha jirka oo aan ahayn limfaha . Inkasta oo dabeecadeeda sii kordheysa, lymphoma Burkitt ayaa badanaa la daaweyn karaa daaweynta casriga ah ee casriga ah.
Noocyada
Waxaa jira laba nooc oo ballaaran oo ah Burkitt's lymphoma - noocyada kala duwan iyo noocyada dareenka. Waxaa jira cudur aad u sarreeya ee cudurkan oo ku yaala bariga afrika, cudurkuna gobolkaasi waxaa loo yaqaan 'lymphoma'. Cudurada gobollada kale ee aduunka waa mid aad u yar waxaana loo yaqaan 'lymphoma'. Inkastoo ay isku mid yihiin, labada noocba way kala duwan yihiin siyaabo badan.
Endemic (Afrika) Burkitt Lymphoma
Dhinaca Afrika ee u dhigma, qiyaastii kala bar dhammaan kansarada carruurnimada waa Burkitt's lymphomas. Cudurku wuxuu ku lug leeyahay carruurta ka weyn dadka waaweyn oo waxay la xiriiraan cudurka Epstein-Barr Virus (EBV) 98% kiisaska. Waxay astaan u leedahay fursada ugu weyn ee ku lug leh jawbone, oo ah qaab muuqaal ah oo aad u yar oo ku yimi barta Burkitt. Sidoo kale waxay ku lug leedahay caloosha.
Gawaarida 'Sportadic Burkitt' ee Lymphoma
Nooca Burkitt ee lymfoma ee saameeya adduunka intiisa kale, oo ay ku jiraan Europe iyo Ameerika waa nooca goosadka ah.
Halkaan sidoo kale, badanaa waa cudur carruurta, oo masuul ka ah qiyaas ahaan saddex meelood oo lymphomas ah carruurta ku nool Mareykanka. Xidhiidhka u dhexeeya Epstein-Barr Virus (EBV) ma ahan mid xooggan oo kala duwan oo kala duwan, inkastoo caddaynta tooska ah ee infakshanka EBV ay ku jiraan hal shantii bukaan ah. In badan oo ka mid ah ka qayb qaadashada qanjirka nudaha, waa caloosha oo si aad ah u saameeya in ka badan 90% carruurta.
Ka-qaybgalka lafaha miskaha ayaa ka badan inta badan ee kala duwanaanta kala duwan. Ka qaybqaadashada Jawaabtu waa mid aad dhif u ah.
Noocyada Aan Isku Dhicin
Labo nooc oo ka mid ah noocyada caadiga ah ee laf-dhabarka Burkitt waxaa ka mid ah:
- Nooca dhexdhexaad ah, oo leh muuqaal ka mid ah labada lafdhabarka burkitto ee Burkitt iyo laf-dhabarka B-cell weyn .
- Xanuunka HIV-da ee la xidhiidha lymphoma, oo la xiriira infakshanka HIV.
Heerarka
Cudurkan waxaa loo jajabin karaa 4 marxaladood oo kala duwan (xusuusta: tani ma aha mid dhameystiran oo waxaa laga yaabaa in ay ku dhejiso xaaladaha qaarkood.)
Marxaladda I - Heerka 1aad waxaa loola jeedaa in kansarku uu ku jiro hal goob oo keliya oo jidhka ah.
Heerka 2aad - Heerka II Burkitt's lymphomas ayaa ku jira meelo ka badan hal goob, laakiin labada gooboodba waxay ku yaalaan hal dhinac oo ka mid ah diaphragm .
Heerka III - Cudurka Halista marxaladda waxaa ku jira qanjidhada ama xarumaha kale ee labada dhinac ee diaphragm.
Heerka IV - Cudurka IV-gu waxaa ka mid ah lymphomas kaas oo laga helayo dhuuxa lafta ama maskaxda (habdhiska dhexe ee dareenka.)
Sababaha iyo Ciladaha Halista ah
Sida kor ku xusan, Epstein-Barr waxay la xiriirtaa inta badan kiisaska foosha 'Burkitt's lymphoma', iyo sidoo kale xaaladaha qaarkood ee xanuunka caadiga ah. Qaadashada difaaca jirka waa arrin khatar ah, iyo Afrika, waxaa loo maleynayaa in duumadu ay carruurta u dejin karto inay noqoto mid u nugul fayraska Epstein-Barr.
Daaweynta
Burkitt's lymphoma waa buro aad u kacsan, oo inta badan nafta halis galiya. Laakiin sidoo kale waa mid ka mid ah qaababka la daaweyn karo ee lymfoma. Si aad u fahamto tani waxay ka caawineysaa in la fahmo in kiimoterapigu ay weerarto unugyada sida ugu dhakhsaha badan leh. Awoodda isticmaalka kiimiko-daweynta ayaa sameeyay qaar ka mid ah lymphoma-ka ugu caansan iyo leukemias ee hore, tan ugu daaweynta iyo suurta galka ah ee la daaweyn karo waqtigan xaadirka ah.
Iyada oo qaababka daweynta ah ee daweynta kemotherabi ee isticmaala daawooyinka qadar sare leh, iyo helitaanka tallaabooyin cusub oo lagu taageerayo shakhsiyaadka inta lagu jiro daweyn degdeg ah, lymphoma waxaa lagu daaweyn karaa bukaanno badan.
Ku dhawaad 80% dadka qaba cudurada degaanka iyo in ka badan kala badh caruurta leh cudur faafa oo badan ayaa la daaweynayaa. Soo noqoshada dabiiciga ah lama arki karo.
Saadaasha
Saadaasha cudurka Burkitt ee lymphoma ee Maraykanka ayaa si muuqata u fiicnaaday sanadihii la soo dhaafay. Intii u dhexeysay 2002 iyo 2008, heerka 5-sano ee badbaadada ayaa ka kacay 71 ilaa 87% carruurta u dhaxeysa dhalashada ilaa da'da 19 sano. Dadka da'doodu u dhaxayso 20 ilaa 39 jirku wuxuu kor u kacay 35 illaa 60%, iyo bukaanka da'doodu ka weyn tahay 40 jir ayaa sidoo kale la hagaajiyay. Laga soo bilaabo waqtigaa sii wanaajin dheeraad ah ee daaweynta, iyo sidoo kale maaraynta waxyeelada soo gaadhay, ayaa dhacay.
La qabsashada
Waxay noqon kartaa argagax in lagu garto lymphoma, iyo xitaa ka sii daran haddii ay tahay ilmahaaga la ogaado. Kordhinta cunuggu wuxuu qaadanayaa tuulo si uu u bilaabo, laakiin waxaad u baahan doontaa nidaamkaaga taageerada ka badan tan wakhti kiiskan. U gee kuwa kale. Kufsigan Tani waa mid aad u yar, laakiin iyada oo la adeegsanayo warbaahinta bulshada, waxaa jira bulsho internet oo firfircoon oo dad ah oo la tacaalaya cudurkaan oo aad la xiriiri karto 24/7 taageerada. Lymphoma iyo ururada caleemaha waxay ku siin karaan caawinaad dheeraad ah oo aad ku sii wadato.
Ilaha
Coghill, A., iyo A. Hildesheim. Epstein-Barr fayrusyada difaaca iyo khatarta la xiriirta malignancies: dib u eegista suugaanta. Somali Journal of Epidemiology . 2014. 180 (7): 687-95.
Costa, L., Xavier, A., Wahlquist, A., iyo E. Hill. Isbedelka ku dhaca noolaanshaha bukaanka qaba Burkitt lymphoma / leukemia ee Maraykanka: falanqeyn lagu sameeyey 3691 xaaladood. Dhiiga . 121 (24): 4861-6.
Dunleavy, K., Pittaluga, S., Shovlin, M, et al. Daaweynta hoose ee xoogga leh ee dadka qaangaarka leh ee leh Burkitt's lymphoma. Wargeyska New England Journal of Medicine . 2013. 369 (20): 1915-25.
Machadka Kansarka Qaranka. Soo-koobista Macluumaadka Kansarka ee PDQ Daaweynta Cudurka Lymphoma ee Ilmaha (Non-Hodgkin Lymphoma Treatment) (PDQ). Tafaasiisha Caafimaadka ee Caafimaadka. 09/29/15. http://www.ncbi.nlm.nih.gov/books/NBK65738/#CDR0000062808__1