20ka sano ee ugu horreeya: 1984-2003
Taariikhda hore ee horumarinta tallaalka HIV wuxuu ahaa mid ka mid ah rajada iyo ballanqaadyada. Waqtigan xaadirka ah fayruska HIV ayaa la ogaaday, saynisyahanno, siyaasiyiinta, iyo dhaqdhaqaaqayaasha ayaa iyaguna la wadaagay oo dhan waxay rumaysteen in tallaalka AIDS-ka uu ku habboon yahay geeska. Waxaa jiray dad diidan, laakiin inta badan waxaa jiray ballamo. Waxay qaadatay sanado badan ka hor rajo ayaa badiyaa lagu beddelay niyad jab. Isticmaal jadwalkan si aad u baratid taariikhda 20-kii sano ee ugu horreeyay ee horumarinta tallaalka HIV.
1984
HIV-1 waa la ogaadaa. AIDS ma aha cudur qarsoodi ah. Cilmi-baadhayaashu waxay bilaabaan inay rajeeyaan inay awood u yeeshaan inay sameeyaan tallaal ka hortagaya cudurrada loo yiqiin sida, iyo waxyaabo kale, "The Plague Gay".
Intii lagu guda jiray shir jaraa'id bishii Abriil, Xoghayaha Caafimaadka Maraykanka Margaret Heckler ayaa sheegay in tallaalka HIV-ga la filayo in la baaro laba sano gudahood.
1985
Horumarka tallaalka ee HIV wuxuu bilaabmaa si macquul ah. Nasiib darro, saynisyahannadu dhibaatooyin ayay ku qabaan. Waxaa soo baxday in HIV-gu uu si aan caadi ahayn loogu habeeyay si looga hortago dariiqooyinka ugu badan ee horumarka tallaalka.
1986
Tallaalka kowaad ee HIV waxaa loo ansixiyey tijaabooyinka kiliinikada.
1987
Maqaalka warbixinta Mawduuca ayaa sheegaya in dhammaan shoogada ay ku jiraan tijaabada tallaalka ay qaadeen HIV-ga inkastoo ay sameeyeen labadaba antibio iyo T-ga oo dhexdhexaadinta jawaabaha difaaca HIV-ga ee ka dib markii la qaatay tallaalka. Dib-u-soocelinta, tani waa fashilmid la'aanta.
Kooxda AIDS Daaweynta Xanuunka Caafimaadka (ACTG) ayaa loo sameeyay si loo bixiyo shabakado goobo caafimaad oo loo isticmaali karo daraasaadka daaweynta HIV.
Imtixaanka koowaad ee kiliinikada tallaalka HIV wuxuu ka bilaabmaa Maraykanka. Xaaladdan I Badbaadinta Cilmi-baarista waxay diiwaan-galisay 138 mutadawiciin ah oo aan si xor ah ufududayn, waxaanay ogaaneysaa in tallaalka murashaxa uusan lahayn waxyeello halis ah.
1988
Kooxda Qiimeeynta Tallaalka ee AIDS-ka (AVEG) waxay billaabmaysaa inay iska qoraan tabaruceyaasha.
1989
Cilmi-baadhayaashu waxay ku dhawaaqeen horumarinta guulaha fayraska SIV-ga (simian immunodeficiency virus) oo ka ilaalisa koox yar oo ka mid ah daan-hayayaasha cudurka.
1990
Maqaal ku yaal magazine Fortune ayaa sheegaya in ay dhici karto in tallaalka HIV-ga looga hortago kahor 1993.
1991
Barnaamijka Pasteur-Merieux Connaught ee barnaamijka tallaalka ee HIV ayaa bilaabmaa.
Talaalka ugu horreeya ee tijaabada ah ee la tijaabiyay AIDS-ka Maraykanka waxaa lagu dhawaaqay ammaan.
Dhammaadka sanadka, 26 patents ayaa loo soo saaray horumarinta tallaalka HIV.
1992
Tijaabinta wajiga labaad ee NIH maaliyadeed ee tallaalka HIV wuxuu bilaabmaa. Waxay qortaa shakhsiyaadka khatarta sare leh waxayna ku taliyaan inay ka fogaadaan dabeecadaha halista ah.
AVEG waxay bilowday tijaabada daaweynta ugu horeysa ee daaweynta - loogu talagalay in lagu yareeyo socodka cudurada halkii looga hortagi lahaa caabuqa bilowgii HIV. Waxay qoreysaa 55 ragga iyo haweenka qaba cudurka HIV.
1993
Tijaabada daaweynta ugu horeysa ee daaweynta ee ay ku jiri karto asymptomatic carruurta infekshanka leh HIV iyo haweenka uurka leh ee HIV qaba ayaa bilaabanaya.
Diiwaanka ugu horreeya ee NIAID ee daaweynta HIV-ga ee lagu qoro dadka qaba cudurrada HIV-ga ee sii kordhaya ayaa bilaabanaya.
Hay'adda Caafimaadka Adduunka iyo Xukuumadda Thailand ayaa ka wada shaqeynaya sidii loo dejin lahaa qorshe qaran oo lagu qiimeeyo tallaalka HIV.
Massachusetts waxay ku dhawaaqday tijaabinta dawlad-goboleed ee ugu horreysa ee tallaalka cudurka dabaysha.
1994
NIH waxay dejisaa tilmaamo ku saabsan ka-qaybgalka dadka laga tirada badan yahay ee tijaabada caafimaadka.
Hawlgallada kowaad ee tijaabada caafimaadka ee Aasiya ayaa soconaya.
1995
Codsiyo guddi talobixin ah oo loo diro tallaalka cudurka dabaysha ee Salk oo loo maro tijaabooyinka wajiga III ee kiliinikada.
1996
Tijaabooyinka wajiga III ee tallaalka Salk, oo hadda loo yaqaan Remune, ayaa bilaabay isqorista Maraykanka iyo Thailand.
Barnaamijka Tallaalka Caalamiga ah ee Tallaalka AIDS-ka (IAVI) ayaa la abuuray.
Garyaqaanka gp160 ayaa si fiican u soo gebogebeeyay, laakiin waxa uu ku fashilmay inuu ka hortago HIV ama uu gaabiyo habka cudurka.
1997
Madaxwaynaha Bill Clinton wuxuu dejinayaa hadafka tallaalka HIV-ga 10 sano gudahood. Inkastoo la hadlaayo koox arday ah oo dhigta jaamacada Morgan State, wuxuu ku dhawaaqay "Ma ahan wax su'aal ah oo ku saabsan in aan samayn karno tallaalka AIDS-ka, waa arrin marmar ah.
Hase yeeshee, isla markiiba ma iman karto, "iyo balanqaad si loo dhiso xarun cilmi-baaris oo tallaal oo HIV-ga ah oo ka socota Machadka Qaranka ee Caafimaadka.
In ka badan 95 tijaabooyinka HIV-ga ayaa la dhameeyay.
In ka badan 2,000 oo rag iyo dumar ah ayaa ka qaybqaatay tijaabooyinka bukaan-socodka tallaalka ee HIV ee goobaha tijaabada ee Qiimeeynta Qiimeeynta Talaalka Aids ee Maraykanka
UNAIDS waxay qabataa kulan si looga wada hadlo arimaha anshaxa ee la xariira samaynta cilmi baarista tallaalka ee dalalka soo koraya.
1998
Vaxgen wuxuu bilaabaa tijaabooyinka wajiga III ee murashaxa tallaalka HIV AIDSVAX.
1999
Guddiga Korjoogteynta Ammaanka Warbixintani waxay dhamaataa tijaabooyinka wajiga 3aad ee marxaladaha kala duwan marka aan wax isbeddel ah laga helin kooxaha tallaalka iyo koox-kooxeedyada.
Uganda waxay noqoneysaa goobta ugu horeysa ee tijaabada tallaalka ee HIV-ga Afrika.
Vaxgen waxay bilowday inay qorato maxkamadeynta AIDSVAX ee Thailand.
2000
Shabakadda Wareegga Tallaalka ee HIV-ga ayaa la sameeyay. HVTN waa iskaashi wadaag-dawladeed oo khuseeya cilmi baarayaasha. Waxay xarunteedu tahay Xarunta Cilmi-Baarista Kansarka ee Fred Hutchinson ee Seattle, oo ay maal-galisay NIH.
UNAIDS waxay soo saartaa dukumenti rasmi ah oo ku saabsan anshaxa cilmi-baadhista tallaalka HIV ee dalalka soo koraya.
Maxkamad ka hortag ah ee HIV-ga ayaa ka bilaabatay Kenya.
Wejiga I ee tijaabada DNA-ga oo qaawan ayaa la bilaabay.
2001
Cilmi baadhayaasha NIH waxay la kulmayaan kooxaha bulshada si ay u sahamiyaan ka qaybgalka dhalinyarada ku jira tijaabooyinka tallaalka HIV.
War-saxaafadeed laga soo saarin May HVTN ayaa ku dhawaaqday in ay haystaan afar tijaabo oo tallaal oo HIV-gu ah, iyada oo mid kalena uu qorshaynayo in uu bilaabo sanadka dambe.
Maxkamad ka socota istiraatijiyada rasmiga ah ee loo yaqaan 'Prime-Boost Strategy' ayaa lagu ogaadey inay muujinayso balanqaadkii daayeerka
2002
AIDSInfo wuxuu tagaa nolol.
GlaxoSmithKline ayaa ku dhawaaqday in ay bilaabi doonto tijaabooyin tallaalka HIV ee diiradda saaraya NefTat iyo gp120.
Merck wuxuu bilaabaa tijaabooyinka badbaadada ee tallaalka gaga.
2003
Waxaa lagu dhawaaqay in maxkamadeynta AIDSVAX ee Thailand ay ku fashilantay.
Tallaalka Epimmune HIV-1090 wuxuu marayaa marxalado tijaabo ah. Talaalku wuxuu ka kooban yahay 21 hab oo loo yaqaan 'DNA-da' oo loo yaqaan 'DNA-da' oo loo yaqaan 'DNA DNA' oo u dhiganta qaybo kala duwan oo fayraska ah oo aad u ilaaliya. Hadafkeedu waa inuu kiciyo jawaab-celinta unugyada cytotoxic T. Waa jadwalka ugu horreeya ee tallaalka AIDS-ka ee lagu barto labadaba labadaba gudaha Maraykanka iyo dibaddaba.
- Fahmidda Cytotoxic T Lymphocytes
Merck iyo Aventis si ay u sameeyaan tijaabada tallaalka gag isku-dhafka ah ee 18 goobood.
Ilaha:Coulter AH "Xaaladda Xaadirka ee Horumarinta Tallaalka: Miyaynu Dhamaan Hore?" Waxay bixisaa Daryeelka Bukaanka. Juun 1992, 6 (3): 123-125.
Deeks SG iyo Walker BD "Xakamaynta Fiiruska Fayraska Nafsadeed ee Aadanaha: Mechanisms of Control Virus Xakamaynta Maqnaanshaha Daaweynta Antiretroviral" Xasaanad. 2007; 27: 406-16.
Dolgin E. "Bartilmaameed cusub ayaa rajeynaya tallaalka HIV" Natiijada Nature. Sibtambar 3. 2009. (Waxaa la helaa internetka 10/1/09)
Miedema F. "Taariikh kooban oo ku saabsan cilmi-baarista tallaalka ee HIV-ga: dib ugu soo noqoshada guddiga sawir qaadidda?" AIDS. 2008 Sep 12; 22 (14): 1699-703.
Murphey-Corb M et al. "Tallaalka SIV-ga oo dhan oo aan fir-fircoonayn ayaa badbaadiya macaques" Science. 1989 Dec 8; 246 (4935): 1293-7.
Walker BD, Burton DR. "Tallaalka AIDS-ka." Sayniska. 2008 Maajo 9, 320 (5877): 760-4.
Dhibaatooyinka Daawooyinka ee Tallaalka Hiv - Xaashida Xaqiiqada ee NIAID. http://www.niaid.nih.gov/factsheets/clinrsch.htm (Abaabulka 10/1/09)
Xaashida Xaqiiqda ee HVTN. http://www.hvtn.org/media/FactSheet.pdf (Abaabulka 10/1/09)
WHO: Kulanka Saddexaad ee Barnaamijka Tallaalka ee AIDS-ka ee Afrika http://www.who.int/mediacentre/news/releases/2005/pr53/en/index.html (Abaabulka 10/1/09)
Liiska Xaqiiqda Tallaalka ee AIDS-ka. http://aidsinfo.nih.gov/Vaccines/MainSearch.aspx?strPreventive=on&strTherapeutic=on&strSponsor=All&strRecruiting=on&status=1&strNoRecruiting=on&NRstatus=1 (Abaabulka 10/1/09)
War-saxaafadeed Warbixinta AIDS-ka: Tallaalka HIV / AIDS-ka http://www.aidsinfo.nih.gov/aprs/release.aspx?an=A00070 (Abaabulka 10/1/09)
Xogta Xaqiiqo ee AEGIS - Cilmi-baarista Rugta HIV / AIDS Tallaalka: www.aegis.org/factshts/NIAID/1997/niaid97_fact_sheet_clinrsch.html (Helitaanka 10/1/09)
TALAALIDA XAALADAHA CAYMISKA AH Waxaa jira rajo dhab ah kadib: Tallaal ka hortag ah wuxuu halkan joogi karaa illaa 1993. Daawooyinka kale ee la heli karo ayaa si dhakhso ah u gaabinaya ama xitaa joojin kara cudurka iyada oo aan wax saameyn ah ku yeelan AZT. Febraayo 26, 1990 Magaaladda Fortune. http://money.cnn.com/magazines/fortune/fortune_archive/1990/02/26/73115/index.htm (Gaaritaan Online 10/1/09)
Warbixinta Tallaalka ee AIDS-ka Qorshaynta Gaarka ah - 2005 Sannadka Dib-u-eegista. Janaayo 2006 • Vol.4 • No.1 http://www.iavi.org/lists/yiipublications/attachments/11b8f27a-4f78-4a9f-9e52-167f3f522901/uabi_vax_table_jan_2006_eng.pdf (Abaabulka 10/1/09)