Synovium, oo loo yaqaan 'membrane synovial', ayaa ah unugyo jilicsan oo jaangoynaya meelaha kala-goysyada diarriyo-yada, kiciska, iyo bursae. Cinjirta jilicsan ayaa dhammaan dhinacyada hoose ee wadajirka ah, marka laga reebo halka laysku daro ee lagu xargagayo kartoonka . Synovium wuxuu leeyahay lakab dibed (subintima) iyo lakab gudaha (intima). Unugyada soodhowrka waxaa lagu magacaabaa synoviocytes.
Waxaa jira laba nooc oo ah synoviocytes, nooca A (macrophage-derived) iyo nooca B (fibroblast-derived). Subintima wuxuu ka kooban yahay mashiinno gudaha ah (gudaha wadajirka), sida maraakiibta dhiigga iyo maraakiibta dabiiciga ah, iyo dareemayaasha. Hoosta lakabka synoviocytes, waxaa ku jira unugyo adipose ama unugyo qasacadeysan. Synovium waa meesha dheecaanka synovial la soo saaro, walaxda saliidda iyo cuno kartoonka iyo lafaha gudaha gudaha capsule.
Synovium ee Rheumatoid Arthritis
Sida cudurrada kale ee rheumatiska, rheumatoid arthritis waa cudur wadajir ah . Xanuunka korontada ee jirka ama xaalad ahaan, nidaamka difaaca jirka , oo caadi ahaan ka caawiya jirkaaga ka ilaalinta caabuqyada iyo cudurada, waxay isku dayaan unugyada wadajirka ah ee loogu talagalay sababo aan la garanayn. Rheumatoid arthritis, unugyada difaaca jirka waxay u safrayaan synovium waxayna bilaabaan infakshan (synovitis). Hannaanka bararka ayaa lagu gartaa kororka unugyada synovial, korriinka dheuubinta, iyo infiltration of unugyada by unugyada inflammatory, oo ay ku jiraan lymphocytes, unugyada plasma, iyo makrophages firfircoon.
Tani waxay muujinaysaa calaamadaha caadiga ah ee rheumatoid arthritis - diirimaad , casaan, barar, iyo xanuun.
Marka rheumatoid arthritis uu sii socdo, synovium oo barara ayaa soo gala oo burburiya naqaska iyo lafta lafta . Muruqyada hareeraha, jooniska, iyo jilicyada taageerada iyo xasilloonida wadajirku waxay noqdaan kuwo daciif ah oo aan awoodin inay si caadi ah u shaqeeyaan.
Dhibaatooyinkaasi waxay keenaan xanuunka wadajirka ah iyo dhaawaca wadajirka ah ee sida caadiga ah lagu arko dadka qaba rheumatoid arthritis. Fahamka waxa ku dhacaya synovium ee rheumatoid arthritis waxay kaa caawineysaa inaad fahamto calaamadaha iyo xanuunka cudurada.
Daaweyn loogu talagalay Iskudhicinta Synovium-bulaacada - Miyuu imanayaa?
Waxaa jiray daneyntii cilmi-baarayaasha ku saabsan horumarinta daaweynta unugyada gaarka ah ee rheumatoid arthritis. Daawooyinka suurtagalka ah, daroogada waxay diirada saari kartaa synovium oo leh karti waxoogaa korodh ah iyada oo la yareeyo jiritaanka sunta. Haddii tani run ahaantii awood u lahaan lahayd, wakiilada imtixaanka waxaa laga yaabaa in loo gudbiyo synovium, taasoo u oggolaaneysa qiimeynta synovitis firfircoon ee isku-dhafan. Inkasta oo ay jireen horumar laga sameeyay aaggan, weli lama helin maqaaxiyaha qaaska ah.
> Ilo:
> Freemont, Anthony J. Pathophysiology of Cartilage iyo Synovium. British Journal of Rheumatology. 1996; 35 (suppl.3.3): 10-13.
> Garrood T. iyo Pitzalis C. Tarjumaada Synovium Inflamed. Quest for Specificity. Arthritis iyo Rheumatism. Abriil 2006.
> Kelley ee buugta qoraalka ee Rheumatology. Qoraalka sagaalaad. Firestein et al. Biyoolojiga Jirrada caadiga ah. Boggaga 8-10.
> O'Connell, John X., MB FRCPC. Baaritaanka Synovium. Somali Journal of Pathology Pathology.
> Smith, Malcolm D. Synovium caadiga ah. Suxufi Roobka Furan. 2011; 5: 100-106.