Down Syndrome iyo Hypothyroidism

Astaamaha, Baaritaanka iyo Daaweynta Hypothyroidism ee Down Syndrome

Down Syndrome iyo Hypothyroidism

Dadka qaba cilladda Down syndrome waxay halis dheeraad ah u tahay inay ku dhacdo hypothyroidism. Hypothyroidism waa cudur la yaab leh oo caadi ah oo saameyn kara dadka da 'kasta leh, waxayna ku dhacaan qiyaas ahaan 1 qof 4,000 oo qof. Xaaladdu waxay ku badan tahay dadka qaba cilladda Down syndrome. Meeshii laga soo bilaabo 13 ilaa 55% dadka qaba cilladda Down syndrome-ka waxay hormarinayaan hypothyroidism inta lagu jiro mudada ay noloshoodu socoto.

Ma cadda sababta dadka qaba cilladda Down syndrome-ka ay fursad weyn u tahay in ay horumariyaan cudurka hypothyroidism. Warka fiicani waa in si fudud loogu daaweyn karo daawada.

Si loo fahmo hypothyroidism, waxaa muhiim ah in la fahmo waxa qanjirku yahay iyo shaqada uu caadi ahaan ku shaqeeyo jirka.

Maxay Tahay Thyroid?

Qanjirkaaga waa qanjaruuji yar oo qaabeysan oo qoorta ku jira oo ku yaala qoortaada, horteeda tufaaxa Adam. Qanjirka 'thyroid' waa qayb ka mid ah habdhiska neefta ama hormoonka. Inkastoo aan caadi ahaan la wadaagno hoormoonnada leh dhalinyarada iyo jinsiga, waxay dhab ahaantii u ciyaaraan door aad u muhiim ah oo lagu xakameynayo waxqabadyada jirka oo ay ka mid yihiin metabolism iyo heerarka tamarta.

Maxay Tahay Hypothyroidism?

Hypothyroidism waa xaalad ay sababto hoormoonka tayroodhka (thyroxine) ee ku jira dhiigga. Marka qof lagu sheego cudurka hypothyroidism, qanjirka 'thyroid' waxaa lagu sheegaa inuu yahay "aan firfircooneyn" - ma keeno hormoon tayo leh oo ku filan.

Astaamaha astaamaha hypothyroidism waxay u eg yihiin calaamadaha iyo astaamaha cilladda Down syndrome-ka , waana ay adkaan kartaa in la sheego faraqa u dhexeeya labada baaritaan. Calaamadaha cudurka hypothyroidism waxaa ka mid ah xaddiga korodhka cuncunka, calool-fadhiga, xanjo ama daal, hoos u dhaca murqaha iyo maqaarka iyo timaha qalalan - wax kasta oo ka dhici kara dadka lagu ogaado cudurka Down syndrome.

Waa maxay maaddada 'thyroid hormone'?

Hormoon Thyroid, oo lagu magacaabo thyroxine, ayaa jirka ku jirta laba foom oo kala duwan oo la yiraahdo T3 iyo T4. T4 waa qaabka ugu caansan ee dhiigga, waxaana loo beddelaa T3 marka uu ka shaqeynayo jirka. Qadarka T4 ee uu soo saaro thyroid waxaa lagu magacaabaa hoormoon loo yaqaan hormoonka kicinta (thyroid stimulating hormone) (TSH). TSH wuxuu kobciyaa qanjidhka si uu u soo saaro T4, ka dibna waxaa loo beddelaa T3 ee jirka. Marka tayroodku uu noqdo mid firfircoon, wuxuu billaabaa soo saarista T4 ka yar baahida jirka. Isku day inaad ku saxdo dhibaatadan, jidhku wuxuu billaabayaa inuu soo saaro wax badan oo ka badan TSH, si loo dardar geliyo qanjirka aan firfircoonayn ee soo saaro hormoonno dheeraad ah. Sidaa daraadeed, in la soo koobo, marka qanjirkaagaagu uu yahay mid aan firfircooneyn, waxaa hoos u dhaca heerarka T4 iyo T3 ee ku jira dhiiggaaga, iyo heerka sare ee TSH.

Sidee Ayuu Looga Dhowaaqaa Cudurka Hypothyroidism ee Dadka qaba Cilladda Down Syndrome?

Sababtoo ah dadka qaba Down syndrome waxay leeyihiin fursad sare si ay u hormarsamaan cudurka "hypothyroidism", waa "baaritaan" ama lagu baaro cudurkaan si joogto ah, baaritaano dhiig ah, oo ku saabsan nolosha noloshooda.

Carruurta badankood ee wadankan jooga, oo leh iyo aan lahayn Cilladda Down syndrome-ka, ayaa lagu baari karaa cudurka hypothyroidism ee dhalmada markay dhalayaan iyada oo loo marayo barnaamijka baaritaanka dhaladka ee gobolka oo dhan.

Haddii baaritaanka maqaarka cusubi uu noqdo mid wanaagsan, ama haddii dhakhtarkaagu uu arko calaamado kale oo ah cudurka hypothyroidism ee dhaladaada cusub isaga ama iyadu waxay ku amri kartaa baadhitaano kale oo dheellitiran si loo xaqiijiyo baadhitaankaas.

Markuu ilmahaagu sii weynaado, isaga ama iyadu waxay sii wadayaan inay baaritaan ku sameeyaan cudurka hypothyroidism. Waxaa lagu talinayaa in dhammaan carruurta qaba Down syndrome lagu baaro hypothyroidism by baaritaano dhiig ah oo qiyaasta heerarka hoormoonka tayroodhka ee lix bilood, hal sano iyo sanad kasta ka dib noloshooda.

Sidee loo daaweeyaa Hypothyroidism?

Hypothyroidism waxaa lagu daaweeyaa iyada oo la baddalayo maqnaanshaha hormoonka tayroodh dabiiciga ah oo leh muuqaal beddel ah oo loo yaqaan 'levothyroxine' (magaca caanka ah ee Synthroid).

Levothyroxine waa kiniin la qaadayo maalin kasta waana in loo qaato inta qof ee nolosha ah. Carruurta qaba hypothyroidism waxaa lagu daaweyn karaa nooc ka mid ah dareeraha levothyroxine ilaa ay ka qaban karaan liqidda kiniinka. Marka qofku bilaabay daaweyn, dhakhtarkooda ayaa sii wadi doona inay kormeeraan heerarka hoormoonka iyo calaamadaha, si loo hubiyo inay helayaan qadarka saxda ah ee levothyroxine.

Khadka hoose

Hypothyroidism waa cudur aad loo daaweyn karo oo badanaa ku dhaca dadka qaba cilladda Down syndrome-ka. Sababtoo ah astaamaha cudurka hypothyroidism waa mid aad u miisaan badan oo isku dhejis qaba Cilladda Down syndrome-ka, dhammaan dadka qaba Down syndrome-ka waa inay leeyihiin dhiigga sannadlaha ah si loo hubiyo haddii ay sameeyeen cudurkaan.

_NOOCA:

_{Akhriska Siyaasadda Maraykanka ee Akhbaarta Cudurada Carruurta. Kormeerka Caafimaadka Carruurta leh Cilladda Down Syndrome. Pediatrics 2001 107: 442-449.}

_{Cohen, W., et al. (1996). Liistada hubinta cudurka Down Syndrome. Warbixinta Kooxda Rabitaanka Caafimaadka ee Down Down Syndrome. Quarterly Down Syndrome. Volume 1 (2).}

_{Selikowitz, Mark. Down Syndrome. New York: Jaamacadda Oxford University. 2008. (Qormada 3aad)}