Daryeelka Daaweynta ee Kansarka Sambabka

by Lynne Eldridge, MD; Waxaa ku jawaabay Grant Hughes, MD

Waa maxay Yoolalka Daryeelka Daryeelka ee Kansarka Sambabka?

Waxaa laga yaabaa inaad maqashay asxaabta iyo kuwa aad jeceshahay kuwaas oo ku jiray daaweynta dayactirka kansarka. Hase yeeshe, daaweynta dayactirka ee kansarka sanbabada ayaa kaliya la eegay oo kaliya dhawaan. Goorma waa daaweynta dayactirka loo isticmaalo kansarka sanbabada iyo maxay yihiin hadafyada daaweynta?

Waa Maxay Daaweeynta Dayactirka?

Ka hor inta aanad bilaabin inaad ka hadasho daawooyinka la isticmaalo, waxay caawimaysaa in ay qeexdo sida dhabta ah ee daaweynta dayactirka.

Daaweynta dayactirku waa nooca daaweynta loo isticmaalo kansarka sambabada sare - gaar ahaan, kobaca unugyada yar ee unugyada sambabada ee unugyada sambabada si loo isku dayo inuu ku wanaajiyo badbaadada, laakiin maaha in la daaweeyo kansarka. Tani waxay ka duwan tahay daaweynta qaar ka mid ah marxaladaha hore ee kansarka sanbabada kaas oo laga yaabo in la siiyo daawo maskaxeed.

Waxaa sidoo kale loo isticmaali karaa marmarka qaarkood dadka qaba kansarka sambabka unugyada yaryar (fiiri hoos.)

Qeexitaanka fudud ee daaweynta dayactirka waa daaweyn joogto ah oo ku saabsan buro aan horay u soo bixin (ka sii dartay) ka dib markii kiimiko hore loo isticmaalo - illaa ay jiraan calaamado muujinaya in kansarku uu sii kordhay (oo sii xumaatay.) Si kale loo dhigo, waa daaweyn la siiyo Ujeedada ah in lagu ilaaliyo buro aan si firfircoon u korin si dhakhso ah, oo aan daaweyn loogu talagalay in lagu yareeyo ama lagu daaweeyo buro.

Yoolalka Daryeelka Daryeelka

Iyadoo daaweyn kasta oo kansar ah ee aad tixgeliso, waxaa muhiim ah in laga fekero hadafyada daaweynta.

Iyadoo tan maskaxda lagu hayo, way sahlan tahay in la miisaamo khatarta daaweynta ee faa'iidooyinka. Hadafka 4aad ee asaasiga ahi waa:

Ka hortagga
Curative
Maareynta Cudurada
Palliative

Daaweynta dayactirka waxaa loo isticmaalaa maareynta cudurka. Maaha mid daaweyn ah, hase yeeshee "wax badan ayuu ka badan yahay daaweynta palliative-ka" oo loogu talagalay inuu sameeyo wax ka badan calaamadaha gargaarka kali ah - himiladiisa waa in la kordhiyo badbaadada iyo tayada nolosha inta lagu jiro badbaadada.

Goorma ayaa la isticmaalaa?

Si loo qeexo daaweynta dabiiciga ah ee kansarka sanbabada, waa isticmaalka daawooyinka ka dib marka qof lagu daaweeyo afar wareeg oo daaweynta kemotherabi ee 'first-line' oo heer sare ah (marxaladda IIIA iyo wareegga IV) kansarka sanbabada haddii kansarku aanu horay u soo bixin muddadan daaweynta. Halka hore, dadka looma daaweynin intaa dheer (halkii taa waxaa raacay wakhti ah " sugid sugid " - taas oo ah, calaamadaha la socoshada iyo raadinta shucaaca si loo arko haddii kansarku korayo), daaweynta dayactirka waxaa loogu talagalay si looga caawiyo calaamadaha kansarka, iyo, waxaan rajeyneynaa wanaajinta wakhti ka badan sidii loo sii wadi lahaa bixinta kiimikada koowaad.

Waxaa jira khilaafyo badan oo ku hareereysan isticmaalka daaweynta dayactirka. Sida daaweyn kasta, saameynaha daaweyntu waxay u baahan tahay in la miisaamo wax faa'iido ah. Iyo - dhaqaaleheena hadda - kharashka sidoo kale waa tixgelin. Daawooyinka loogu talagalay "dayactirka" waxay noqon karaan kuwo qaali ah. Daraasadaha qaarkood waxay muujinayaan oo kaliya waxoogaa horumarin yar oo badbaadin ah (oo ah maalmo dhowr toddobaad ah inta badan), qoysaska badanaaba waa ay ka tageen iyada oo miisaamaya horumarin aad u hooseeya oo lagu noolaado culeyska dhaqaale ee daaweynta.

Waa maxay Daawooyinka loo Isticmaalo?

Waqtiga xaadirka ah, waxaa jira laba dawo oo ay ansixiyeen FDA si loogu daweeyo daaweynta kansarka sambabada sare.

Daawooyin kale oo dhowr ah (iyo isu-geynta daawooyinka) ayaa lagu baranayaa tijaabooyinka bukaan socodka . Daawooyinka la oggol yahay waxaa ka mid ah:

Alimta (tobankii sanno) - Sanadkii 2009, FDA waxay ogolaatay isticmaalka Alimta ee daaweynta dayactirka ee kansarka sanbabada.
Tarceva (erlotinib) - FDA waxay ogolaatay Tarceva inay u isticmaasho daaweynta dayactirka kansarka sanbabada sannadkii 2010.

Yaa ka faa'iideysta inta badan?

Sida daaweynta ugu badan ee kansarka sanbabada, waxaa jira dadka qaarkood oo ka jawaab celiya wax ka badan kuwa kale daaweynta.

Cilmi-baarista Alimta waxay muujisay inay u muuqato in ay wax ku ool u tahay dadka qaba sambabada adenocarcinoma iyo kansarka sambabka ee unugyada waaweyn. Waxa kale oo ay u muuqataa in ay wax ku ool u tahay dadka leh isbedel EGFR .

Cilmi-baarista Tarceva ayaa sidoo kale muujisay in ay sii wanaajinayaan noloshooda ugu horayntii dadka qaba kansarka sanbabada unugyada yaryar ee aan lahayn kaansarka sanbabada unugyada. Waxa kale oo ay u muuqataa in ay ka faa'iideysanayaan dadka mutaddawiciinta EGFR si ka sarreeya kuwa aan haysan isbeddelka. Faa'idada ugu weyn ee badbaadada ee daaweynta dayactirka Tarceva waxaa loo heley dumar aan weligood sigaar cabin kuwaas oo caafimaad ahaan guud ahaan jiray marka laga reebo waqtiga daaweynta.

Saameynta iyo Dhibaatooyinka

Daryeelka Daaweynta ee Kansarka Cudurka Sambabka Kufsigu Dheeraad ah

Iyadoo daaweynta dabiiciga ah loo isticmaalo kowaad ee kansarka sambabada unugyada yaryar, tijaabooyinka dhawaan la sameeyay ayaa waxay soo jeedinayaan in ay door ka qaadan karto marxaladda weyn ee kansarka sambabada unugyada yar ee sambabada oo hoos u riixaya, iyada oo leh isbeddel dhinaca hagaajinta noolaanshaha dadka lagu daaweeyo sunitinib dayactirka iyo daaweynta caanaha duufaan.

Taageerida iyo Kaalinta

Waxa la sheegay in mid ka mid ah "saameynaha" ee daaweynta dabiiciga ah ay tahay in dadku aanay helin dareen ah inay daaweyn dhamaystirto. Si kale haddii loo dhigo, ma dareemayaan "kuwa ka badbaaday." Waxay ku caawin kartaa in maskaxda lagu hayo in daaweynta hormoonnada ee daaweynta kansarka naasku ay noqoto mid loo arko daaweynta dayactirka sidoo kale, dadka badankood ee ku dhacay kansarka naasuhu waxay sii wadaan qaadashada daaweynta hormoonnada, ha noqoto tamoxifen ama aromatase inhibitor ah marka ay dhammeeyaan daaweynta kansarka . Waxa kale oo ay caawin kartaa in la xasuusiyo dhamaanteena qeexitaanka ee ka-badbaadaha kansarka: qofku waa ka-badbaadaha kansarka laga bilaabo xilliga lagu ogaado cudurka, iyo inta ka dhiman noloshooda.

Waxay u badan tahay in la daaweeyo kansarka sanbabada kansarka sanbabada oo labadaba sii kordhaya tirada dadka isticmaala daawadan iyo muhiimada ay leedahay. Fikradda ayaa ah inaan bilaabeyno inaan daweyno kansarka sanbabada intaa ka badan oo ah sida cudur dabadheeraad ah . Ma hubin karno dadka badankood, laakiin cudurku waxa uu rajeyn karaa in la xakameeyo muddo dheer.

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Waa Maxay Daaweeynta Dayactirka?

Yoolalka Daryeelka Daryeelka

Goorma ayaa la isticmaalaa?

Waa maxay Daawooyinka loo Isticmaalo?

Yaa ka faa'iideysta inta badan?

Saameynta iyo Dhibaatooyinka

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