Nidaamka Nidaamka Nidaamka Isku-xirnaanta ee MS
Hiddahaaga ayaa muhiim u ah in aad halis u tahay inuu ku dhaco MS , sida ay u taageeraan labada qoys iyo daraasad cilmiyeed.
Daraasaadka Qoyska oo Cadaynaya in Cuncaddaha Cayaartu ku Caawinayso MS
Dadka guud ahaan, waxaa jira 1 fursad 750 (boqolkiiba 0.1) fursad uu qofku ku dhici doono MS. Hase yeeshee, labada qof ee qaba MS waxay leeyihiin qiyaastii 25 ilaa iyo 40 boqolkiiba fursadda ah in uu ku dhaco MS, walaalaha walaalaha lehna waxay leeyihiin 3 ilaa 5 fursad.
Daraasadaha sayniska sida caddaynaya in genes ciyaaraha kaalinta ee MS
Daraasad 2007-kii lagu daabacay Wargayska New England Journal ayaa heshay saameyn cusub oo ku saabsan hidde-wade (MS). Daraasadan ayaa muujinaysa in dadka qaba noocyo kala duwan oo ah laba gen oo kala duwan oo ku lug leh nidaamka difaaca jirka (IL7RA iyo IL2RA) ay u badan tahay in ay qabaan MS marka la barbar dhigo dadka aan isku dhufanayn.
IZ7RA iyo IL2RA waa borotiin kuwaas oo hagaya ficilada nooc ka mid ah unugyada difaaca jirka (unugyada T). Iyadoo la fiiriyo sida borotiinka lagu sameeyo jidhka, isbeddelka nooca borotiinka wuxuu u taagan yahay farqiga genetics.
Nooca MS-la xiriira ee borotiinka ayaa laga yaabaa in ay ka caawiso MS iyaga oo hagaya unugyada difaaca si ay u weeraraan nidaamka dareemayaasha, taas oo horseedaysa demyelination iyo dhaawacyada maskaxda iyo xudunta lafdhabarta. Dhibaatadan, markaa, waxay keenaysaa noocyo badan oo calaamadaha MS ah . Arrinta xiisaha leh, isku-dhafnaanta IL2R ayaa lala xiriiriyay nooca 1aad ee sonkorowga iyo cudurka Graves, iyo sidoo kale xanuunada mareenka .
Dhowr kale oo daraasado kale ah ayaa taageera xiriirka u dhaxeeya MS iyo hidaha ee xakameynaya nidaamka difaaca jirka. Qaybta khafiifka ah ayaa ah inay jiraan waxyaabo badan oo isbeddel ah oo hidde ah, oo lagu qiyaasay 50 ilaa 100 by National MS Society, taas oo lagu go'aamiyo halista ah in uu ku dhaco MS iyo haddii ay ku dhacaan MS, sida ay u daran tahay.
Falanqaynta xogta MS-ga ayaa ah mid adag oo waqti-badan, laakiin qiimo leh, gaar ahaan haddii ay ka fiicnaan karto hababka MS-ga.
Khadka hoose
Waxaa muhiim ah in la fahmo in inkastoo hiddo-qabaduhu ay door muhiim ah ka ciyaaraan horumarka MS iyo suurta galnimada koorsada ay raacayso, ma aha wax walba. Si kale haddii loo dhigo, MS ma aha cudur si toos ah u dhaxeeya, markaa ma jirto damaanad ah inaadan doonayn ama aadan ka heleynin taariikhda qoyskaaga (ama koodhkaaga sheygaaga).
Taa baddalkeeda, habka uu MS-gu u kobciyo uguna muuqdo qofku waxa uu noqon karaa mid adag, oo ku lug leh jilicsanaanta u dhexaysa hidaha qofka iyo deegaanka. Tusaale ahaan, isbeddello isdaba-joog ah ayaa dhici karta in qofku u nugulaado inuu horumariyo MS markii uu soo gaadhay dabeecad gaar ah, sida fayraska (inkastoo, ma garanayno kuwa hufan ee aan weli hayn).
Waqtigaan hadda, dhakhaatiirtu ma samaynayaan baaritaanka hidda-socodka ee dadka qaba MS ama xubnaha qoyska ee leh MS. Hase yeeshee, sida cilmi-baarista hidde-galka MS (horay u dhaqso badan), daaweyntu way kala duwanaan kartaa iyada oo ku saleysan shakhsiyaadka sheyga gaarka ah ee qofka.
Ilaha:
Gourraud, PA, Harbo, HF, Hauser, SL, & Baranzini, SE (2012). Cudurka qanjirada "multiple sclerosis": dib u eegis taariikhda ah. Imtixaanka Immunological , Jul: 248 (1): 87-103.
Iskuduwaha Caalamiga ah ee "Sclerosis Sclerosis Consortium", iyo al. (2007). Khatarta khatarta ah ee cudurka sclerosis ee lagu aqoonsado daraasad isdaba joog ah. Journal of Medicine New England, Aug 30; 357 (9): 851-62.
Society MS Society. Ayaa Yeelanayaa MS? (Epidemiology).
Society MS Society. Xaqiiqooyinka asaasiga ah: Genetics.
Sadovnick, AD, iyo al. (1993). Daraasad dadweyne ku salaysan oo ku saabsan xawaaro badan oo mataano ah: cusbooneysiin. Annals of Neurology, Mar; 33 (3): 281-5.