Naafooyinka Naafada ah ee Saameeya Nidaamyada Kala Duwan
Costello syndrome waa cudur aad u yar kaas oo saameeya nidaamyo badan oo jirka ah, taas oo keenta caato gaaban, muuqaalada muuqaalka dabeecadda, koritaanka sanka iyo afka, iyo dhibaatooyinka wadnaha. Sababta loo yaqaan "Costello syndrome" lama yaqaan, in kastoo isbedelka hidde-wade lagu tuhunsan yahay. Sannadkii 2005 cilmi-baadhayaasha Isbitaalka DuPontal ee Carruurta ee Delaware (US) waxay heleen isbeddellada hiddaha ee HRAS oo isugu jira 82.5% oo ka mid ah 40 qof oo qaba Costello syndrome ah.
Keliya 150 warar oo ku saabsan Costello syndrome ayaa lagu daabacay wargeysyada caafimaadka adduunka oo dhan, sidaa daraadeed ma cadda sida ay badanaa cilladuhu u dhacaan ama cidda ay u badan tahay inay saameyn ku yeelato.
Astaamaha
Calaamadaha caadiga ah ee loo yaqaan "Costello syndrome" waa:
- Dhibaatada miisaanka koritaanka iyo korniinka dhalashada ka dib, taas oo horseedaysa heer gaaban
- maqaarka oo si xad dhaaf ah u qoorta, qoryaha gacmaha, faraha, iyo cagaha cagaha (cutis laxa)
- kobaca aan lahayn kansarka (papillomata) agagaarka afkiisa iyo sanka
- muuqaal muuqaal oo muuqaal ah sida madax ballaaran, dhegaha yar-yar oo leh dhejiyo waaweyn, dhumuc qaro weyn leh, dibnaha qaro weyn, iyo / ama sankooda ballaaran
- niyad jab maskaxeed
- maqaarka engegsan, gacmaha iyo cagaha ama gacmaha iyo lugaha (hyperkeratosis)
- si aan caadi ahayn oo is dabajoog ah ee faraha.
Shakhsiyaadka qaarkood ayaa laga yaabaa inay xakameeyaan dhaqdhaqaaqa suxulka ama adkeynta maskaxda dhabarka dambe ee canqowga. Shakhsiyaadka qaba Costello syndrome waxay yeelan karaan cillado wadnaha ah ama cudurka wadnaha (kardiomyopathy).
Waxaa jira dhacdooyin aad u sarreeya koritaanka bukaanka, labadaba kansar iyo kuwa aan kansar ahayn, oo la xiriira cudurka dabeecadda.
Ciladeynta
Ciladda tayada "Costello syndrome" waxay ku saleysan tahay muuqaalka muuqaalka cunugga ee ku dhasha xanuunka, iyo sidoo kale astaamaha kale ee laga yaabo inay joogaan. Carruurta intooda ugu badan ee qaba cudurka kansarka waxay ku adkaataa quudinta, iyo sidoo kale helitaanka miisaan iyo korriin, sidaas darteed tani waxay soo jeedin kartaa ogaanshaha.
Mustaqbalka, baaritaanka hidda-socodka loogu talagalay isbeddellada hiddaha ee la xiriirta Costello syndrome ayaa loo isticmaali karaa si loo xaqiijiyo ogaanshaha cudurka.
Daaweynta
Ma jiro daaweyn khaas ah oo loogu talagalay Costello syndrome, sidaa darteed daryeel caafimaad ayaa diiradda saaraya calaamadaha iyo jirrada. Waxaa lagu talinayaa in dhammaan shakhsiyaadka qaba Costello syndrome ay helaan helitaanka qiimeynta wadnaha si loo raadsado cilladaha wadnaha iyo / ama wadnaha. Daaweyn jireed iyo shaqeyn ayaa ka caawin kara qofku inuu gaaro himiladiisa koritaankiisa. Kormeer joogto ah oo loogu talagalay korriimada bukaanka, lafdhabarta ama dhibaatooyinka orthopedic, iyo isbedelka wadnaha ama dhiig karka ayaa muhiim ah. Nolosha qofka leh Costello syndrome ayaa saameyn ku yeelan kara jiritaanka wadnaha wadnaha ama burooyinka kansarka , markaa haddii ay caafimaad qabaan, shakhsiyaadka qaba cudurkaasi waxay yeelan karaan nolol caadi ah.
> Ilo:
> Costello Kids. Ku saabsan Costello syndrome.
> Gripp, KW, et al. (2005). Falanqaynta isbeddelka HRAS ee ku jira Costello syndrome: Cudurka jinsiga (genotype) iyo ciladda feylka. Somali Journal of Genetics Medical.
> Lin, AE, et al. (2002). Faahfaahin dheeraad ah oo ku saabsan cilladaha wadnaha ee Costello syndrome. Somali Journal of Genetics Medical, 111 (2), bogga 115-129.
> Moroni, I, et al. (2000). Costello Syndrome: Cudurka kansarka ee xanuunka qaba? Clin Dysmorphol, 9 (4), bogga 265-268.
> Ururka Qaran ee Cudurka Naaska. Costello Syndrome.
> Pascual-Castroviego, I., iyo al. (2005). Costello syndrome: Soo bandhigida kiis la socosho 35 sano ah. Neurologia, 20 (3), bogga 144-148.